open access

Vol 60, No 5 (2009)
Review paper
Submitted: 2013-02-15
Published online: 2009-10-30
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Chromogranin A (CgA) - characteristic of the currently available laboratory methods and conditions which can influence the results

Piotr Glinicki, Wojciech Jeske
Endokrynol Pol 2009;60(5):415-419.

open access

Vol 60, No 5 (2009)
Reviews — Postgraduate Education
Submitted: 2013-02-15
Published online: 2009-10-30

Abstract

Chromogranin A is a main, nonspecific neuroendocrine tumor marker (NET). It’s estimation was applied for diagnostic purposes and for monitoring the treatment of NET. Currently few commercial assays are available allowing measurement of CgA concentration in serum or plasma. These methods have various sensitivity and specificity and differ in many analitycal parameters. Numerous factors and pathologies may influence the outcome of the CgA measurement. Therefore, a review article on this matter may be useful for clinical and laboratory practice.

Abstract

Chromogranin A is a main, nonspecific neuroendocrine tumor marker (NET). It’s estimation was applied for diagnostic purposes and for monitoring the treatment of NET. Currently few commercial assays are available allowing measurement of CgA concentration in serum or plasma. These methods have various sensitivity and specificity and differ in many analitycal parameters. Numerous factors and pathologies may influence the outcome of the CgA measurement. Therefore, a review article on this matter may be useful for clinical and laboratory practice.
Get Citation

Keywords

chromogranin A; CgA-IRMA; CgA-RIA; CgA-ELISA; neuroendocrine tumors

About this article
Title

Chromogranin A (CgA) - characteristic of the currently available laboratory methods and conditions which can influence the results

Journal

Endokrynologia Polska

Issue

Vol 60, No 5 (2009)

Article type

Review paper

Pages

415-419

Published online

2009-10-30

Page views

494

Article views/downloads

15464

Bibliographic record

Endokrynol Pol 2009;60(5):415-419.

Keywords

chromogranin A
CgA-IRMA
CgA-RIA
CgA-ELISA
neuroendocrine tumors

Authors

Piotr Glinicki
Wojciech Jeske

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