The role of osteoprotegerin and witamin D in thyroid pathology

Dominika Tuchendler; Marek Bolanowski

Vol 60, No 6 (2009)

Review paper

Submitted: 2013-02-15

Published online: 2009-12-30

View PDF (Polish)

Download PDF file

Get Citation

The role of osteoprotegerin and witamin D in thyroid pathology

Dominika Tuchendler, Marek Bolanowski

Endokrynol Pol 2009;60(6):470-475.

Vol 60, No 6 (2009)

Review Article

Submitted: 2013-02-15

Published online: 2009-12-30

Abstract

Hormonal dysfunction of thyroid gland manifests, among other, in bone tissue disorders. The evaluation of changes in bone is possible not only by using the classical markers of bone turnover. Very interesting chemical compounds are osteoprotegerin and vitamin D; their serum concentration among patients with thyroid disorders can show the range of changes in bone metabolism. Osteoprotegerin possess an ability of reduction of bone resorption. Vitamin D has several "nonclassical" mechanisms of action, also the possibility of interaction with endogenous thyroid hormones. The aim of this study is to review the current literature concerning the role of osteoprotegerin and vitamin D in thyroid pathology.