Vol 60, No 6 (2009)
Review paper
Published online: 2009-12-30
The role of osteoprotegerin and witamin D in thyroid pathology
Endokrynol Pol 2009;60(6):470-475.
Abstract
Hormonal dysfunction of thyroid gland manifests, among other, in bone tissue disorders. The evaluation of changes in bone is possible not
only by using the classical markers of bone turnover. Very interesting chemical compounds are osteoprotegerin and vitamin D; their serum
concentration among patients with thyroid disorders can show the range of changes in bone metabolism. Osteoprotegerin possess an
ability of reduction of bone resorption. Vitamin D has several "nonclassical" mechanisms of action, also the possibility of interaction with
endogenous thyroid hormones. The aim of this study is to review the current literature concerning the role of osteoprotegerin and vitamin
D in thyroid pathology.
Keywords: osteoptotegerinvitamin Dhyperthyroidismhypothyroidism
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