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Vol 60, No 6 (2009)
Case report
Submitted: 2013-02-15
Published online: 2009-12-30
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Difficulties in the diagnosis of ACTH-dependent Cushing’s syndrome in a patient after left adrenalectomy and treated with glucocorticoids

Barbara Brzezińska, Roman Junik, Anna Kamińska, Grzegorz Zieliński
DOI: 10.5603/ep.25433
·
Endokrynol Pol 2009;60(6):484-487.

open access

Vol 60, No 6 (2009)
Case report
Submitted: 2013-02-15
Published online: 2009-12-30

Abstract

Cushing’s syndrome (CS), that is a consequence of chronic excess of corticosteroides, is most frequently of iatrogenic origin. Corticotropin secreting pituitary adenomas are responsible for most cases of endogenous Cushing’ s syndrome. Difficulties in the diagnosis and treatment of ACTH-dependent Cushing’s syndrome concern with localization of the source of pathological ACTH secretion, particularly when magnetic resonance imaging is unable to identify the pituitary microadenoma.
In this paper we present the case of a patient with symptoms of Cushing’s syndrome and describe problems with localization of the source of hypercortisolemia.The diagnostic process was additionally complicated by the treatment with corticosteroids, ocassionally applied due to concomitant diseases. This delayed the right diagnosis and treatment.

Abstract

Cushing’s syndrome (CS), that is a consequence of chronic excess of corticosteroides, is most frequently of iatrogenic origin. Corticotropin secreting pituitary adenomas are responsible for most cases of endogenous Cushing’ s syndrome. Difficulties in the diagnosis and treatment of ACTH-dependent Cushing’s syndrome concern with localization of the source of pathological ACTH secretion, particularly when magnetic resonance imaging is unable to identify the pituitary microadenoma.
In this paper we present the case of a patient with symptoms of Cushing’s syndrome and describe problems with localization of the source of hypercortisolemia.The diagnostic process was additionally complicated by the treatment with corticosteroids, ocassionally applied due to concomitant diseases. This delayed the right diagnosis and treatment.

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Keywords

Cushing’s syndrome; diagnosis; treatment

About this article
Title

Difficulties in the diagnosis of ACTH-dependent Cushing’s syndrome in a patient after left adrenalectomy and treated with glucocorticoids

Journal

Endokrynologia Polska

Issue

Vol 60, No 6 (2009)

Article type

Case report

Pages

484-487

Published online

2009-12-30

Page views

441

Article views/downloads

6085

DOI

10.5603/ep.25433

Bibliographic record

Endokrynol Pol 2009;60(6):484-487.

Keywords

Cushing’s syndrome
diagnosis
treatment

Authors

Barbara Brzezińska
Roman Junik
Anna Kamińska
Grzegorz Zieliński

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