open access

Vol 60, No 6 (2009)
Original papers
Published online: 2009-12-30
Submitted: 2013-02-15
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Comparison of thyroid volume and goiter measured by means of ultrasonography and SPECT with use of 131I and 99mTc in smokers and non-smokers

Marcin Gierach, Joanna Gierach, Roman Junik
Endokrynologia Polska 2009;60(6):437-442.

open access

Vol 60, No 6 (2009)
Original papers
Published online: 2009-12-30
Submitted: 2013-02-15

Abstract


Introduction: The aim of the study was to estimate the influence of nicotine on thyroid volume according to patients’ sex.
Material and methods: A group of 160 patients with thyroid disorders in their past medical history was examined. Patients were divided into two groups: Group A contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and 131I-SPECT; group B contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and 99mTc-SPECT. There were two control groups: Group A’ contained 30 patients with normal volume of the thyroid gland shown by US and 131I-SPECT, and group B’ contained 30 patients with normal volume of the thyroid gland shown by US and 99mTc-SPECT. The patients from the examined and control groups were divided into two subgroups - smokers and non-smokers. US of the thyroid gland was made by means of an ALOKA SSD 500 device. SPECT was performed by means of a singke-headed gamma camera by Diacam.
Results: The average volume of thyroid gland measured by 131I-SPECT and 99mTc-SPECT was significantly larger according to US in the examined and control groups in smokers and non-smokers. We did not show statistically significant correlations between levels of iodine uptake and volumes of goiter evaluated by US examination together with 131I scintigraphy.
Conclusions: Significant differences in average values of thyroid volume between smokers and non-smokers were not observed, which might suggest a lack of goitrogenic activity of tobacco smoke or indicates a potential goitrogenic influence not significant enough in the examined group.

Abstract


Introduction: The aim of the study was to estimate the influence of nicotine on thyroid volume according to patients’ sex.
Material and methods: A group of 160 patients with thyroid disorders in their past medical history was examined. Patients were divided into two groups: Group A contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and 131I-SPECT; group B contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and 99mTc-SPECT. There were two control groups: Group A’ contained 30 patients with normal volume of the thyroid gland shown by US and 131I-SPECT, and group B’ contained 30 patients with normal volume of the thyroid gland shown by US and 99mTc-SPECT. The patients from the examined and control groups were divided into two subgroups - smokers and non-smokers. US of the thyroid gland was made by means of an ALOKA SSD 500 device. SPECT was performed by means of a singke-headed gamma camera by Diacam.
Results: The average volume of thyroid gland measured by 131I-SPECT and 99mTc-SPECT was significantly larger according to US in the examined and control groups in smokers and non-smokers. We did not show statistically significant correlations between levels of iodine uptake and volumes of goiter evaluated by US examination together with 131I scintigraphy.
Conclusions: Significant differences in average values of thyroid volume between smokers and non-smokers were not observed, which might suggest a lack of goitrogenic activity of tobacco smoke or indicates a potential goitrogenic influence not significant enough in the examined group.
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Keywords

goiter; thyroid; US; SPECT

About this article
Title

Comparison of thyroid volume and goiter measured by means of ultrasonography and SPECT with use of 131I and 99mTc in smokers and non-smokers

Journal

Endokrynologia Polska

Issue

Vol 60, No 6 (2009)

Pages

437-442

Published online

2009-12-30

Bibliographic record

Endokrynologia Polska 2009;60(6):437-442.

Keywords

goiter
thyroid
US
SPECT

Authors

Marcin Gierach
Joanna Gierach
Roman Junik

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