open access

Vol 61, No 3 (2010)
Original papers
Published online: 2010-07-02
Submitted: 2013-02-15
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High prevalence of goiter in schoolchildren in Isfahan; zinc deficiency does not play a role

Ammar Hassanzadeh Keshteli, Mahin Hashemipour, Mansour Siavash, Roya Kelishadi, Masoud Amini
Endokrynologia Polska 2010;61(3):287-290.

open access

Vol 61, No 3 (2010)
Original papers
Published online: 2010-07-02
Submitted: 2013-02-15

Abstract


Introduction: There are controversial data about the role of zinc deficiency in the aetiology of endemic goiter. The aim of the present study was to determine the association between zinc status and goiter in schoolchildren of Isfahan.
Material and methods: This study was performed in 2005. Two thousand three hundred and thirty-one schoolchildren were enrolled, and thyroid size was determined by inspection and palpation. Urinary iodine concentration (UIC) and serum zinc level were measured in a group of those children.
Results: The prevalence of goiter was 32.9%. The median UIC was 195.5 μg/L. Serum zinc was measured in 94 goitrous and 326 nongoitrous children. The mean ± standard deviation of serum zinc in goitrous and non-goitrous children was 100.81 ± 22.33 and 96.00 ± 25.79 μg/dL, respectively (P = 0.08). The prevalence of zinc deficiency (serum zinc ≤ 65 μg/dL) in goitrous and non-goitrous children did not differ significantly (6.4 % v. 8.0%, P = 0.61).
Conclusions: The prevalence of goiter is still high in Isfahan schoolchildren. It seems that zinc status is not involved in the high prevalence of goiter in this region. The role of other possible goitrogens should be investigated in Isfahan.
(Pol J Endocrinol 2010; 61 (3): 287–290)

Abstract


Introduction: There are controversial data about the role of zinc deficiency in the aetiology of endemic goiter. The aim of the present study was to determine the association between zinc status and goiter in schoolchildren of Isfahan.
Material and methods: This study was performed in 2005. Two thousand three hundred and thirty-one schoolchildren were enrolled, and thyroid size was determined by inspection and palpation. Urinary iodine concentration (UIC) and serum zinc level were measured in a group of those children.
Results: The prevalence of goiter was 32.9%. The median UIC was 195.5 μg/L. Serum zinc was measured in 94 goitrous and 326 nongoitrous children. The mean ± standard deviation of serum zinc in goitrous and non-goitrous children was 100.81 ± 22.33 and 96.00 ± 25.79 μg/dL, respectively (P = 0.08). The prevalence of zinc deficiency (serum zinc ≤ 65 μg/dL) in goitrous and non-goitrous children did not differ significantly (6.4 % v. 8.0%, P = 0.61).
Conclusions: The prevalence of goiter is still high in Isfahan schoolchildren. It seems that zinc status is not involved in the high prevalence of goiter in this region. The role of other possible goitrogens should be investigated in Isfahan.
(Pol J Endocrinol 2010; 61 (3): 287–290)
Get Citation

Keywords

Goiter; zinc deficiency; iodine deficiency; Iran

About this article
Title

High prevalence of goiter in schoolchildren in Isfahan; zinc deficiency does not play a role

Journal

Endokrynologia Polska

Issue

Vol 61, No 3 (2010)

Pages

287-290

Published online

2010-07-02

Bibliographic record

Endokrynologia Polska 2010;61(3):287-290.

Keywords

Goiter
zinc deficiency
iodine deficiency
Iran

Authors

Ammar Hassanzadeh Keshteli
Mahin Hashemipour
Mansour Siavash
Roya Kelishadi
Masoud Amini

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