Vol 61, No 4 (2010)
Case report
Published online: 2010-08-31
Postpartum hypothalamic dysfunction - a case report
Endokrynol Pol 2010;61(4):396-399.
Abstract
Hypothalamic dysfunction is a rarely diagnosed endocrine disorder resulting from various pathological processes affecting this brain
region. It is characterized by a complex clinical manifestation, including headaches, abnormal regulation of various behaviours, abnormalities
in sleeping and thermoregulation, and inappropriate secretion of many hormones. In our paper, we report the case of a 29-year-old
female in whom hypothalamic dysfunction was induced by delivery complications. Accurate diagnosis of this syndrome required complex
laboratory and imaging tests. The disease-related obesity was resistant to conventional treatment (diet and pharmacotherapy) and
only bariatric surgery caused a reduction of body mass. The described patient is the first with postpartum hypothalamic dysfunction in
whom plasma levels of adipokines, neuropeptides, and alimentary tract hormones contributing to physiological regulation of food intake
were assessed. (Pol J Endocrinol 2010; 61 (4): 396-399)
Keywords: postpartum hypothalamic dysfunctionclinical pictureobesitypathogenesistreatment
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