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Vitamin D status of 6- to 7-year-old children living in Isfahan, Iran
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Abstract
Introduction: Vitamin D is essential for the maintenance of good health, and vitamin D deficiency has been reported from many countries, including those with a lot of sunshine. This study was conducted to evaluate the vitamin D status in healthy 6- to 7-year-old children in Isfahan, Iran.
Material and methods: Five hundred and thirteen healthy children were enrolled. Serum PTH and 25-hydroxyvitamin D (25-OHD) were measured. Dietary vitamin D intake, duration of daily sunlight exposure, and percentage of exposed body surface area were determined. 25-OHD levels < 20 ng/mL and < 10 ng/mL were defined as mild and severe vitamin D deficiency, respectively. The ROC curve was utilized to obtain a local cut-off point of vitamin D deficiency.
Results: 25-OHD was < 20 ng/mL in 3% and < 33 ng/mL (local cut-off point of vitamin D deficiency) in 26% of subjects. Duration of sunlight exposure and daily intake of vitamin D had significant effects on serum level of vitamin D.
Conclusions: A high prevalence of vitamin D deficiency in Isfahan children was observed in this study. Improvements in duration of sunlight exposure and daily intake of vitamin D can prevent vitamin D deficiency in these children. (Pol J Endocrinol 2010; 61 (4): 377-382)
Abstract
Introduction: Vitamin D is essential for the maintenance of good health, and vitamin D deficiency has been reported from many countries, including those with a lot of sunshine. This study was conducted to evaluate the vitamin D status in healthy 6- to 7-year-old children in Isfahan, Iran.
Material and methods: Five hundred and thirteen healthy children were enrolled. Serum PTH and 25-hydroxyvitamin D (25-OHD) were measured. Dietary vitamin D intake, duration of daily sunlight exposure, and percentage of exposed body surface area were determined. 25-OHD levels < 20 ng/mL and < 10 ng/mL were defined as mild and severe vitamin D deficiency, respectively. The ROC curve was utilized to obtain a local cut-off point of vitamin D deficiency.
Results: 25-OHD was < 20 ng/mL in 3% and < 33 ng/mL (local cut-off point of vitamin D deficiency) in 26% of subjects. Duration of sunlight exposure and daily intake of vitamin D had significant effects on serum level of vitamin D.
Conclusions: A high prevalence of vitamin D deficiency in Isfahan children was observed in this study. Improvements in duration of sunlight exposure and daily intake of vitamin D can prevent vitamin D deficiency in these children. (Pol J Endocrinol 2010; 61 (4): 377-382)
Keywords
vitamin D status; vitamin D deficiency; Iran; diet; sunlight
About this articleTitle
Vitamin D status of 6- to 7-year-old children living in Isfahan, Iran
Journal
Issue
Article type
Original paper
Pages
377-382
Published online
2010-08-31
Page views
1017
Article views/downloads
1709
DOI
10.5603/ep.25366
Bibliographic record
Endokrynol Pol 2010;61(4):377-382.
Keywords
vitamin D status
vitamin D deficiency
Iran
diet
sunlight
Authors
Pooneh Memar Ardestani
Mehdi Salek
Ammar Hassanzadeh Keshteli
Hossein Nejadnik
Masoud Amini
Seyyed Mehdi Hosseini
Homayoun Rafati
Roya Kelishadi
Mahin Hashemipour
