open access

Vol 61, No 6 (2010)
Review paper
Submitted: 2013-02-15
Published online: 2010-11-15
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Vitamin D supplementation in adults - guidelines

Ewa Marcinowska-Suchowierska, Magdalena Walicka, Marek Tałałaj, Wanda Horst-Sikorska, Magdalena Ignaszak-Szczepaniak, Ewa Sewerynek
Endokrynol Pol 2010;61(6):723-729.

open access

Vol 61, No 6 (2010)
Reviews — Postgraduate Education
Submitted: 2013-02-15
Published online: 2010-11-15

Abstract

Vitamin D is necessary in maintaining appropriate calcium and phosphate homeostasis in the body (classical function) and ensuring appropriate functioning of many tissues, organs and cells, unrelated to mineral economy (non-classical function). Vitamin D deficiency in adults may cause osteomalacia, increase fracture risk in osteoporosis, induce cardiovascular diseases, diabetes type 1 and 2, multiple sclerosis, Lesniowski-Crohn disease, and cancer, including colon, breast, and prostate cancer.
Possible causes of vitamin D deficiency in a healthy population include decreased cutaneous synthesis and an inadequate intake of vitamin D, both in food and in supplements. Vitamin D deficiency level (25(OH) D. < 20 ng/mL), is fairly widespread, being found in a substantial percentage of healthy subjects around the world, regardless of race, gender and age. Daily vitamin D dose, as determined by the Food and Nutrition Board in 1997, is now rather insufficient, the biggest problem being associated with maximal vitamin D levels (50 μg/day) in actually available food supplements. Nowadays, it is recommended that adults need a minimum of 800–1,000 U/day when their exposure to the sun is inadequate (in Poland from October to April). This dosage should be provided to all subjects who avoid sunlight, as well as to those aged over 65 because of their slower skin synthesis of vitamin D and for its proven anti-fracture and anti-fall effects.
(Pol J Endocrinol 2010; 61 (6): 723-729)

Abstract

Vitamin D is necessary in maintaining appropriate calcium and phosphate homeostasis in the body (classical function) and ensuring appropriate functioning of many tissues, organs and cells, unrelated to mineral economy (non-classical function). Vitamin D deficiency in adults may cause osteomalacia, increase fracture risk in osteoporosis, induce cardiovascular diseases, diabetes type 1 and 2, multiple sclerosis, Lesniowski-Crohn disease, and cancer, including colon, breast, and prostate cancer.
Possible causes of vitamin D deficiency in a healthy population include decreased cutaneous synthesis and an inadequate intake of vitamin D, both in food and in supplements. Vitamin D deficiency level (25(OH) D. < 20 ng/mL), is fairly widespread, being found in a substantial percentage of healthy subjects around the world, regardless of race, gender and age. Daily vitamin D dose, as determined by the Food and Nutrition Board in 1997, is now rather insufficient, the biggest problem being associated with maximal vitamin D levels (50 μg/day) in actually available food supplements. Nowadays, it is recommended that adults need a minimum of 800–1,000 U/day when their exposure to the sun is inadequate (in Poland from October to April). This dosage should be provided to all subjects who avoid sunlight, as well as to those aged over 65 because of their slower skin synthesis of vitamin D and for its proven anti-fracture and anti-fall effects.
(Pol J Endocrinol 2010; 61 (6): 723-729)
Get Citation

Keywords

vitamin D; food inadequacy; supplementation

About this article
Title

Vitamin D supplementation in adults - guidelines

Journal

Endokrynologia Polska

Issue

Vol 61, No 6 (2010)

Article type

Review paper

Pages

723-729

Published online

2010-11-15

Page views

1059

Article views/downloads

2755

Bibliographic record

Endokrynol Pol 2010;61(6):723-729.

Keywords

vitamin D
food inadequacy
supplementation

Authors

Ewa Marcinowska-Suchowierska
Magdalena Walicka
Marek Tałałaj
Wanda Horst-Sikorska
Magdalena Ignaszak-Szczepaniak
Ewa Sewerynek

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