open access

Vol 61, No 6 (2010)
Case report
Published online: 2010-11-15
Submitted: 2013-02-15
Get Citation

An elderly diabetic case of ochronosis with depression and chronic pain

Mehmet Ilkin Naharci, Mehmet Ak, Ergun Bozoglu, Nuri Karadurmus, Ahmet Turan Isik, Huseyin Doruk
Endokrynologia Polska 2010;61(6):710-713.

open access

Vol 61, No 6 (2010)
Case report
Published online: 2010-11-15
Submitted: 2013-02-15

Abstract

Alkaptonuria (ochronosis) is a rare autosomal recessive disorder featuring a genetic error in the amino acid metabolism. A defect in the tyrosine metabolism results in the accumulation and deposition of homogentisic acid in connective tissue, causing a blue-black discolouration. Degenerative arthropathy of the spine, knee, and hip are common signs of ochronosis in older age. An association between ochronosis and depression has not previously been discussed in the literature. This case report describes a 69 year-old woman with diabetes mellitus, ochronosis, depression and chronic pain.
(Pol J Endocrinol 2010; 61 (6): 710-713)

Abstract

Alkaptonuria (ochronosis) is a rare autosomal recessive disorder featuring a genetic error in the amino acid metabolism. A defect in the tyrosine metabolism results in the accumulation and deposition of homogentisic acid in connective tissue, causing a blue-black discolouration. Degenerative arthropathy of the spine, knee, and hip are common signs of ochronosis in older age. An association between ochronosis and depression has not previously been discussed in the literature. This case report describes a 69 year-old woman with diabetes mellitus, ochronosis, depression and chronic pain.
(Pol J Endocrinol 2010; 61 (6): 710-713)
Get Citation

Keywords

alkaptonuria; chronic pain; depression; elderly; ochronosis; diabetes mellitus

About this article
Title

An elderly diabetic case of ochronosis with depression and chronic pain

Journal

Endokrynologia Polska

Issue

Vol 61, No 6 (2010)

Pages

710-713

Published online

2010-11-15

Bibliographic record

Endokrynologia Polska 2010;61(6):710-713.

Keywords

alkaptonuria
chronic pain
depression
elderly
ochronosis
diabetes mellitus

Authors

Mehmet Ilkin Naharci
Mehmet Ak
Ergun Bozoglu
Nuri Karadurmus
Ahmet Turan Isik
Huseyin Doruk

Important: This website uses cookies.tanya dokter More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Via MedicaWydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl