open access

Vol 61, No 6 (2010)
Original papers
Published online: 2010-11-15
Submitted: 2013-02-15
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Inhibin B and FSH as markers of Sertoli cell function in impaired spermatogenesis

Marek Mędraś, Anna Trzmiel-Bira, Paweł Jóźków, Łukasz Terpiłowski, Ewa Zagocka, Teresa Sicińska-Werner
Endokrynologia Polska 2010;61(6):695-698.

open access

Vol 61, No 6 (2010)
Original papers
Published online: 2010-11-15
Submitted: 2013-02-15

Abstract


Introduction: The relationships between inhibin B, FSH and sperm count have never been fully elucidated. Our aim was to search for associations between serum concentrations of inhibin B/FSH and the impairment of spermatogenesis.
Material and methods: In an observational study, we compared sperm count, serum levels of inhibin B and FSH in men with oligozoospermia (n = 46) and in normozoospermic, fertile controls (n = 38).
Results: Concentration of FSH was 10.27 &#177; 11.24 IU/L in the oligozoospermic and 3.84 &#177; 2.76 IU/L in the normospermic group (p < 0.01). Although the concentration of inhibin B was higher in the oligozoospermic group (424 &#177; 443 v. 297 &#177; 219 pg/mL), the difference was statistically insignificant.
Conclusions: Our results suggest that there is a tendency toward increased serum inhibin B levels in subjects with altered sperm count and increased serum FSH.
(Pol J Endocrinol 2010; 61 (6): 695-698)

Abstract


Introduction: The relationships between inhibin B, FSH and sperm count have never been fully elucidated. Our aim was to search for associations between serum concentrations of inhibin B/FSH and the impairment of spermatogenesis.
Material and methods: In an observational study, we compared sperm count, serum levels of inhibin B and FSH in men with oligozoospermia (n = 46) and in normozoospermic, fertile controls (n = 38).
Results: Concentration of FSH was 10.27 &#177; 11.24 IU/L in the oligozoospermic and 3.84 &#177; 2.76 IU/L in the normospermic group (p < 0.01). Although the concentration of inhibin B was higher in the oligozoospermic group (424 &#177; 443 v. 297 &#177; 219 pg/mL), the difference was statistically insignificant.
Conclusions: Our results suggest that there is a tendency toward increased serum inhibin B levels in subjects with altered sperm count and increased serum FSH.
(Pol J Endocrinol 2010; 61 (6): 695-698)
Get Citation

Keywords

inhibin B; FSH; sperm count; Sertoli cell; idiopathic oligozoospermia

About this article
Title

Inhibin B and FSH as markers of Sertoli cell function in impaired spermatogenesis

Journal

Endokrynologia Polska

Issue

Vol 61, No 6 (2010)

Pages

695-698

Published online

2010-11-15

Bibliographic record

Endokrynologia Polska 2010;61(6):695-698.

Keywords

inhibin B
FSH
sperm count
Sertoli cell
idiopathic oligozoospermia

Authors

Marek Mędraś
Anna Trzmiel-Bira
Paweł Jóźków
Łukasz Terpiłowski
Ewa Zagocka
Teresa Sicińska-Werner

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