Atypical subtrochanteric fractures after long-term bisphosphonate therapy

Edward Czerwiński

Vol 62, No 1 (2011)

Review paper

Submitted: 2013-02-15

Published online: 2011-03-01

View PDF

Download PDF file

Get Citation

Atypical subtrochanteric fractures after long-term bisphosphonate therapy

Edward Czerwiński

Endokrynol Pol 2011;62(1):84-87.

Vol 62, No 1 (2011)

Review Article

Submitted: 2013-02-15

Published online: 2011-03-01

Abstract

There have been many reports published in recent years on atypical subtrochanteric fractures after long-term bisphosphonates therapy. In a description of a few series of cases, fractures of typical clinical course and radiological image have been documented. These fractures are estimated as very rare (2.3 per 10,000 patient-years). It is suggested that a subsequent use of steroids or proton pump inhibitors with bisphosphonates may increase the risk of fracture occurrence. (Pol J Endocrinol 2011; 62 (1): 84-87)