Vol 62, No 1 (2011)
Review paper
Published online: 2011-03-01

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Atypical subtrochanteric fractures after long-term bisphosphonate therapy

Edward Czerwiński
Endokrynol Pol 2011;62(1):84-87.


There have been many reports published in recent years on atypical subtrochanteric fractures after long-term bisphosphonates therapy. In a description of a few series of cases, fractures of typical clinical course and radiological image have been documented. These fractures are estimated as very rare (2.3 per 10,000 patient-years). It is suggested that a subsequent use of steroids or proton pump inhibitors with bisphosphonates may increase the risk of fracture occurrence. (Pol J Endocrinol 2011; 62 (1): 84-87)

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