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Involvement of the auditory organ in type 1 diabetes mellitus
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Abstract
Material and methods: Thirty-one patients with type 1 diabetes, aged below 45 years (mean 29.1 ± 7.1 years), with diabetes duration of less than 120 months (mean 54.7 ± 32.5 months), and no evident hearing impairment, were compared to 26 age-matched (30.3 ± 7.8 years, p = 0.567) healthy volunteers. In all subjects, pure-tone audiometry, transient evoked otoacoustic emissions (TEOAE), and auditory brainstem responses (ABR) were performed, after an ENT examination.
Results: In diabetic patients, compared to healthy subjects, the mean hearing threshold in the pure-tone audiometry was significantly higher at high frequencies, the mean amplitude of TEOAE was lower (7.75 ± 4.43 dB v. 10.00 ± 4.01 dB, p < 0.001), and latency times of wave V and interval I–V in ABR were longer (5.78 ± 0.25 ms v. 5.69 ± 0.18 ms, p = 0.025 and 4.03 ± 0.20 ms v. 3.95 ± 0.17 ms, p = 0.017 respectively). In the diabetic group, the hearing threshold showed positive linear correlation with age, whereas TEOAE was inversely correlated with this parameter. In ABR latency, times of wave V and interval I–V were negatively correlated with diabetes duration.
Conclusions: This study confirms the involvement of the auditory organ in type 1 diabetes mellitus. To determine the prognostic and predictive values of this finding, and methods of possible prevention of hearing loss, further prospective observations are required.
(Pol J Endocrinol 2011; 62 (2): 138–144)
Abstract
Material and methods: Thirty-one patients with type 1 diabetes, aged below 45 years (mean 29.1 ± 7.1 years), with diabetes duration of less than 120 months (mean 54.7 ± 32.5 months), and no evident hearing impairment, were compared to 26 age-matched (30.3 ± 7.8 years, p = 0.567) healthy volunteers. In all subjects, pure-tone audiometry, transient evoked otoacoustic emissions (TEOAE), and auditory brainstem responses (ABR) were performed, after an ENT examination.
Results: In diabetic patients, compared to healthy subjects, the mean hearing threshold in the pure-tone audiometry was significantly higher at high frequencies, the mean amplitude of TEOAE was lower (7.75 ± 4.43 dB v. 10.00 ± 4.01 dB, p < 0.001), and latency times of wave V and interval I–V in ABR were longer (5.78 ± 0.25 ms v. 5.69 ± 0.18 ms, p = 0.025 and 4.03 ± 0.20 ms v. 3.95 ± 0.17 ms, p = 0.017 respectively). In the diabetic group, the hearing threshold showed positive linear correlation with age, whereas TEOAE was inversely correlated with this parameter. In ABR latency, times of wave V and interval I–V were negatively correlated with diabetes duration.
Conclusions: This study confirms the involvement of the auditory organ in type 1 diabetes mellitus. To determine the prognostic and predictive values of this finding, and methods of possible prevention of hearing loss, further prospective observations are required.
(Pol J Endocrinol 2011; 62 (2): 138–144)
Keywords
type 1 diabetes; hearing impairment; pure-tone audiometry; otoacoustic emissions; auditory brainstem responses
Title
Involvement of the auditory organ in type 1 diabetes mellitus
Journal
Issue
Article type
Original paper
Pages
138-144
Published online
2011-04-29
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681
Article views/downloads
1377
Bibliographic record
Endokrynol Pol 2011;62(2):138-144.
Keywords
type 1 diabetes
hearing impairment
pure-tone audiometry
otoacoustic emissions
auditory brainstem responses
Authors
Mariusz Dąbrowski
Grażyna Mielnik-Niedzielska
Andrzej Nowakowski