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Vol 62, No 3 (2011)
Case report
Submitted: 2013-02-15
Published online: 2011-06-29
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Primary pigmented nodular adrenocortical disease

Harris Abdullah Ngow, Wan Mohd Nowalid Wan Khairina
DOI: 10.5603/ep.25275
·
Endokrynol Pol 2011;62(3):268-270.

open access

Vol 62, No 3 (2011)
Case report
Submitted: 2013-02-15
Published online: 2011-06-29

Abstract

Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenal tumour causing corticotrophin-independent Cushing’s syndrome. It occurs mainly in children and young adults. The histological examination is characterised by small pigmented micronodules on the adrenal cortex. The diagnosis is most often seen in patients with Carney Complex, but it can also occur in isolation. We report a case of Carney Complex that was referred for adrenalectomy. The procedure was uneventful and the patient was well at discharge. The adrenal pathology showed numerous black nodules measuring less than 2mm in diameter. This feature was pathognomonic of primary pigmented nodular adrenocortical disease. (Pol J Endocrinol 2011; 62 (3): 268–270)

Abstract

Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenal tumour causing corticotrophin-independent Cushing’s syndrome. It occurs mainly in children and young adults. The histological examination is characterised by small pigmented micronodules on the adrenal cortex. The diagnosis is most often seen in patients with Carney Complex, but it can also occur in isolation. We report a case of Carney Complex that was referred for adrenalectomy. The procedure was uneventful and the patient was well at discharge. The adrenal pathology showed numerous black nodules measuring less than 2mm in diameter. This feature was pathognomonic of primary pigmented nodular adrenocortical disease. (Pol J Endocrinol 2011; 62 (3): 268–270)

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Keywords

PPNAD; Carney complex; adrenal gland; tumour

About this article
Title

Primary pigmented nodular adrenocortical disease

Journal

Endokrynologia Polska

Issue

Vol 62, No 3 (2011)

Article type

Case report

Pages

268-270

Published online

2011-06-29

Page views

509

Article views/downloads

1355

DOI

10.5603/ep.25275

Bibliographic record

Endokrynol Pol 2011;62(3):268-270.

Keywords

PPNAD
Carney complex
adrenal gland
tumour

Authors

Harris Abdullah Ngow
Wan Mohd Nowalid Wan Khairina

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