open access

Vol 62, No 6 (2011)
Original papers
Published online: 2011-12-06
Submitted: 2013-02-15
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Laparoscopic adrenalectomy for functioning and non-functioning adrenal tumours

Jerzy Lubikowski, Bartosz Kiedrowicz, Mikołaj Szajko, Elżbieta Andrysiak-Mamos, Sławomir Pynka, Maciej Wójcicki, Konrad Jarosz, Monika Koziołek, Henryk Fuchs, Mariola Post, Krzysztof Safranow, Anhelli Syrenicz
Endokrynologia Polska 2011;62(6):512-516.

open access

Vol 62, No 6 (2011)
Original papers
Published online: 2011-12-06
Submitted: 2013-02-15

Abstract

Background: The purpose of this study was a retrospective analysis of outcomes following laparoscopic adrenalectomy (LA) performed for benign adrenal tumours responsible for various endocrinological disorders. The patients were diagnosed with non-functioning (NFT) and functioning adrenal tumours (FT) including pheochromocytoma (PH), Conn’s syndrome (CO) and Cushing’s (CS) syndrome.
Material and methods: A total of 165 LAs were carried out between August 1995 and September 2009 via either the transperitoneal (n = 38) or retroperitoneal (n = 127) approach. The analysed factors included demographic data of patients, the American Association of Anaesthesiology score (ASA), indication for surgery, tumour size and side, intraoperative and postoperative outcome of LA including duration of surgery, blood loss, time until ambulation, length of hospital stay, time until return to normal activity, the complication rate, as well as the conversion rate to open adrenalectomy.
Results: There were 111 patients with NFT and 54 with FT. Patients with NFT were significantly older than those with CO (p < 0.05). The mean size of the lesion differed between CO and other adrenal tumours (p < 0.05) as well as between NFT and PH (p < 0.05). All the lesions except aldosteronomas were detected predominantly in the right adrenal gland (p < 0.05). However, despite the different characteristic and clinical disorders related to laparoscopically removed adrenal tumours, the intraoperative and postoperative outcomes did not significantly differ in most cases between the analysed groups of patients.
Conclusion: This study shows that LA is a safe, effective, and well-tolerated procedure despite the hormonal activity of the removed lesions. Minimal invasive surgery may be recommended as the ‘gold standard’ in the treatment of both functioning and non-functioning benign tumours of the adrenal gland. (Pol J Endocrinol 2011; 62 (6): 512–516)

Abstract

Background: The purpose of this study was a retrospective analysis of outcomes following laparoscopic adrenalectomy (LA) performed for benign adrenal tumours responsible for various endocrinological disorders. The patients were diagnosed with non-functioning (NFT) and functioning adrenal tumours (FT) including pheochromocytoma (PH), Conn’s syndrome (CO) and Cushing’s (CS) syndrome.
Material and methods: A total of 165 LAs were carried out between August 1995 and September 2009 via either the transperitoneal (n = 38) or retroperitoneal (n = 127) approach. The analysed factors included demographic data of patients, the American Association of Anaesthesiology score (ASA), indication for surgery, tumour size and side, intraoperative and postoperative outcome of LA including duration of surgery, blood loss, time until ambulation, length of hospital stay, time until return to normal activity, the complication rate, as well as the conversion rate to open adrenalectomy.
Results: There were 111 patients with NFT and 54 with FT. Patients with NFT were significantly older than those with CO (p < 0.05). The mean size of the lesion differed between CO and other adrenal tumours (p < 0.05) as well as between NFT and PH (p < 0.05). All the lesions except aldosteronomas were detected predominantly in the right adrenal gland (p < 0.05). However, despite the different characteristic and clinical disorders related to laparoscopically removed adrenal tumours, the intraoperative and postoperative outcomes did not significantly differ in most cases between the analysed groups of patients.
Conclusion: This study shows that LA is a safe, effective, and well-tolerated procedure despite the hormonal activity of the removed lesions. Minimal invasive surgery may be recommended as the ‘gold standard’ in the treatment of both functioning and non-functioning benign tumours of the adrenal gland. (Pol J Endocrinol 2011; 62 (6): 512–516)
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Keywords

laparoscopic adrenalectomy; functioning adrenal tumours; non-functioning adrenal tumours

About this article
Title

Laparoscopic adrenalectomy for functioning and non-functioning adrenal tumours

Journal

Endokrynologia Polska

Issue

Vol 62, No 6 (2011)

Pages

512-516

Published online

2011-12-06

Bibliographic record

Endokrynologia Polska 2011;62(6):512-516.

Keywords

laparoscopic adrenalectomy
functioning adrenal tumours
non-functioning adrenal tumours

Authors

Jerzy Lubikowski
Bartosz Kiedrowicz
Mikołaj Szajko
Elżbieta Andrysiak-Mamos
Sławomir Pynka
Maciej Wójcicki
Konrad Jarosz
Monika Koziołek
Henryk Fuchs
Mariola Post
Krzysztof Safranow
Anhelli Syrenicz

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