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Vol 63, No 2 (2012)
Review paper
Submitted: 2013-02-15
Published online: 2012-04-27
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Adipocytokines and sex hormone disorders in patients with chronic renal failure (CRF)

Stanisław Niemczyk, Katarzyna Romejko-Ciepielewska, Longin Niemczyk
DOI: 10.5603/ep.25188
·
Endokrynol Pol 2012;63(2):148-155.

open access

Vol 63, No 2 (2012)
Reviews — Postgraduate Education
Submitted: 2013-02-15
Published online: 2012-04-27

Abstract

The authors discussed disorders in adipocytokines’ function in chronic renal failure (CRF) and their clinical implications. Adipocytokines’ concentrations in CRF are in most cases elevated, which is associated with decreased level of their excretion. This may cause number of clinical implications such as inflammation, loss of appetite, development of protein energy wasting (PEW) syndrome and the progress of artherosclerosis, what leads to increased mortality in a group of patients with end-stage renal disease (ESRD). Disturbances in sexual hormones function are also characteristic for CRF. Disorders in fertility, sexual life and decreased quality of life are observed in patients with CRF. Therapeutic procedure is complicated and not fully effective. (Pol J Endocrinol 2012; 63 (2): 148–155)

Abstract

The authors discussed disorders in adipocytokines’ function in chronic renal failure (CRF) and their clinical implications. Adipocytokines’ concentrations in CRF are in most cases elevated, which is associated with decreased level of their excretion. This may cause number of clinical implications such as inflammation, loss of appetite, development of protein energy wasting (PEW) syndrome and the progress of artherosclerosis, what leads to increased mortality in a group of patients with end-stage renal disease (ESRD). Disturbances in sexual hormones function are also characteristic for CRF. Disorders in fertility, sexual life and decreased quality of life are observed in patients with CRF. Therapeutic procedure is complicated and not fully effective. (Pol J Endocrinol 2012; 63 (2): 148–155)

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Keywords

renal failure; adipocytokines; leptin; adiponectin; resistin; visfatin; sex hormones

About this article
Title

Adipocytokines and sex hormone disorders in patients with chronic renal failure (CRF)

Journal

Endokrynologia Polska

Issue

Vol 63, No 2 (2012)

Article type

Review paper

Pages

148-155

Published online

2012-04-27

Page views

571

Article views/downloads

4268

DOI

10.5603/ep.25188

Bibliographic record

Endokrynol Pol 2012;63(2):148-155.

Keywords

renal failure
adipocytokines
leptin
adiponectin
resistin
visfatin
sex hormones

Authors

Stanisław Niemczyk
Katarzyna Romejko-Ciepielewska
Longin Niemczyk

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