Vol 63, No 2 (2012)
Case report
Submitted: 2013-02-15
Published online: 2012-04-27
Mediastinal parathyroid carcinoma: a case report
Jacek Gawrychowski, Andrzej Gabriel, Ewa Kluczewska, Grzegorz Buła, Bożena Lackowska
DOI: 10.5603/ep.25186
·
Endokrynol Pol 2012;63(2):143-146.
Vol 63, No 2 (2012)
Case report
Submitted: 2013-02-15
Published online: 2012-04-27
Abstract
A 72 year-old woman with primary hyperparathyroidism was operated for parathyroid crisis. PTH serum level was 808 pg/mL. During
the operation, only two superior parathyroid glands were found. One was normal, and hypertrophy was revealed in the other. After the
surgical procedure, PTH serum level was 726.5 pg/mL. Helical computer tomography examination showed a heterogeneous mass in the
anterior mediastinum. The tumour was removed via a sternotomy approach. Histopathological examination revealed parathyroid carcinoma.
PTH level dropped to 5.74 pg/mL. Cytofluorometric examination revealed diploidy (DI = 1) in both the hypertrophic and the unchanged
upper glands, whereas parathyroid cancer was aneuploid. After the initial operation, the woman was discharged from the hospital on the
27th postoperative day. One year after surgical procedures, she is well. She has to take calcium. (Pol J Endocrinol 2012; 63 (2): 143–146)
Abstract
A 72 year-old woman with primary hyperparathyroidism was operated for parathyroid crisis. PTH serum level was 808 pg/mL. During
the operation, only two superior parathyroid glands were found. One was normal, and hypertrophy was revealed in the other. After the
surgical procedure, PTH serum level was 726.5 pg/mL. Helical computer tomography examination showed a heterogeneous mass in the
anterior mediastinum. The tumour was removed via a sternotomy approach. Histopathological examination revealed parathyroid carcinoma.
PTH level dropped to 5.74 pg/mL. Cytofluorometric examination revealed diploidy (DI = 1) in both the hypertrophic and the unchanged
upper glands, whereas parathyroid cancer was aneuploid. After the initial operation, the woman was discharged from the hospital on the
27th postoperative day. One year after surgical procedures, she is well. She has to take calcium. (Pol J Endocrinol 2012; 63 (2): 143–146)
Keywords
mediastinal parathyroid carcinoma; DNA ploidy
Title
Mediastinal parathyroid carcinoma: a case report
Journal
Endokrynologia Polska
Issue
Vol 63, No 2 (2012)
Article type
Case report
Pages
143-146
Published online
2012-04-27
Page views
573
Article views/downloads
1600
DOI
10.5603/ep.25186
Bibliographic record
Endokrynol Pol 2012;63(2):143-146.
Keywords
mediastinal parathyroid carcinoma
DNA ploidy
Authors
Jacek Gawrychowski
Andrzej Gabriel
Ewa Kluczewska
Grzegorz Buła
Bożena Lackowska