open access

Vol 63, No 3 (2012)
Original papers
Published online: 2012-06-28
Submitted: 2013-02-15
Get Citation

Is vitamin D deficiency an independent risk factor for obesity and abdominal obesity in women?

Gonca Tamer, Banu Mesci, Ismet Tamer, Damla Kilic, Safiye Arik
Endokrynologia Polska 2012;63(3):196-201.

open access

Vol 63, No 3 (2012)
Original papers
Published online: 2012-06-28
Submitted: 2013-02-15

Abstract

Introduction: Vitamin D has been determined to have some effects on b cell function and insulin sensitivity, and it is known that type 2 diabetes mellitus and hyperparathyroidism can cause obesity. The aim of our study was to investigate if vitamin D deficiency without diabetes mellitus and metabolic syndrome is associated with obesity and abdominal obesity.
Material and methods: The study included 276 healthy premenopausal women. To exclude other causes of obesity, postmenopausal women and subjects with diabetes mellitus and metabolic syndrome were excluded. Women were divided into two groups depending on their 25-hydroxyvitaminD3 [25(OH)D3] levels: subjects with vitamin D deficiency (Group 1) and subjects without vitamin D deficiency (Group 2). Body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) were compared between the two groups.
Results: BMI, WC, WHR, rates of obesity, and abdominal obesity according to WC and WHR of Group 2 were lower than those of Group 1 (p = 0.0005, p = 0.0001, p = 0.0045, p = 0.032, p = 0.002, p = 0.011, respectively). 25(OH)D3 levels negatively correlated with BMIs (r = &#8211;0.480, p < 0.0001), WCs (r = &#8211;0.480, p < 0.0001) and WHRs (r = &#8211;0.312, p < 0.05). There were no differences between serum parathormone, calcium and phosphorus levels of Group 1 and 2 (p = 0.239, p = 0.354, p = 0.95, respectively).
Conclusion: Vitamin D deficiency without diabetes mellitus and hyperparathyroidism may be associated with obesity and abdominal obesity.

Abstract

Introduction: Vitamin D has been determined to have some effects on b cell function and insulin sensitivity, and it is known that type 2 diabetes mellitus and hyperparathyroidism can cause obesity. The aim of our study was to investigate if vitamin D deficiency without diabetes mellitus and metabolic syndrome is associated with obesity and abdominal obesity.
Material and methods: The study included 276 healthy premenopausal women. To exclude other causes of obesity, postmenopausal women and subjects with diabetes mellitus and metabolic syndrome were excluded. Women were divided into two groups depending on their 25-hydroxyvitaminD3 [25(OH)D3] levels: subjects with vitamin D deficiency (Group 1) and subjects without vitamin D deficiency (Group 2). Body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) were compared between the two groups.
Results: BMI, WC, WHR, rates of obesity, and abdominal obesity according to WC and WHR of Group 2 were lower than those of Group 1 (p = 0.0005, p = 0.0001, p = 0.0045, p = 0.032, p = 0.002, p = 0.011, respectively). 25(OH)D3 levels negatively correlated with BMIs (r = &#8211;0.480, p < 0.0001), WCs (r = &#8211;0.480, p < 0.0001) and WHRs (r = &#8211;0.312, p < 0.05). There were no differences between serum parathormone, calcium and phosphorus levels of Group 1 and 2 (p = 0.239, p = 0.354, p = 0.95, respectively).
Conclusion: Vitamin D deficiency without diabetes mellitus and hyperparathyroidism may be associated with obesity and abdominal obesity.
Get Citation

Keywords

obesity; abdominal obesity; vitamin D deficiency; 25-hydroxyvitaminD3; body mass index

About this article
Title

Is vitamin D deficiency an independent risk factor for obesity and abdominal obesity in women?

Journal

Endokrynologia Polska

Issue

Vol 63, No 3 (2012)

Pages

196-201

Published online

2012-06-28

Bibliographic record

Endokrynologia Polska 2012;63(3):196-201.

Keywords

obesity
abdominal obesity
vitamin D deficiency
25-hydroxyvitaminD3
body mass index

Authors

Gonca Tamer
Banu Mesci
Ismet Tamer
Damla Kilic
Safiye Arik

Important: This website uses cookies.tanya dokter More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Via MedicaWydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl