open access

Vol 63, Supp. II (2012)
Review paper
Submitted: 2013-02-15
Published online: 2012-12-31
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Primary aldosteronism: a common and important problem. A practical guide to the diagnosis and treatment

Janusz Myśliwiec, Maria Górska

open access

Vol 63, Supp. II (2012)
Reviews — Postgraduate Education
Submitted: 2013-02-15
Published online: 2012-12-31

Abstract

In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Polish Society of Endocrinology has recently published recommendations on the diagnosis and management of PA. Due to the fact that the currently available tests cannot be considered the gold standard in the diagnosis of PA and the discrepancies in the results of determination of aldosterone levels and plasma renin activity (PRA) are considerable the authors of this document do not provide strict cutoff values, leaving the interpretation of results to clinicians. This paper, which focuses on screening and confirmatory tests and on the aetiological diagnosis and treatment of PA, is based on the experience of the Department of Endocrinology, Diabetes and Internal Diseases, Medical University in Bialystok, Poland, but it also takes into account other points of view presented in papers published in the past few years. (Endokrynol Pol 2012; 63 (education supplement II) 1–14)

Abstract

In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Polish Society of Endocrinology has recently published recommendations on the diagnosis and management of PA. Due to the fact that the currently available tests cannot be considered the gold standard in the diagnosis of PA and the discrepancies in the results of determination of aldosterone levels and plasma renin activity (PRA) are considerable the authors of this document do not provide strict cutoff values, leaving the interpretation of results to clinicians. This paper, which focuses on screening and confirmatory tests and on the aetiological diagnosis and treatment of PA, is based on the experience of the Department of Endocrinology, Diabetes and Internal Diseases, Medical University in Bialystok, Poland, but it also takes into account other points of view presented in papers published in the past few years. (Endokrynol Pol 2012; 63 (education supplement II) 1–14)
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Keywords

plasma aldosterone concentration; plasma renin activity; aldosterone-renin ratio; confirmatory tests

About this article
Title

Primary aldosteronism: a common and important problem. A practical guide to the diagnosis and treatment

Journal

Endokrynologia Polska

Issue

Vol 63, Supp. II (2012)

Article type

Review paper

Pages

1-14

Published online

2012-12-31

Page views

661

Article views/downloads

6382

Keywords

plasma aldosterone concentration
plasma renin activity
aldosterone-renin ratio
confirmatory tests

Authors

Janusz Myśliwiec
Maria Górska

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