Vol 63, Supp. II (2012)
Review paper
Published online: 2012-12-31
Primary aldosteronism: a common and important problem. A practical guide to the diagnosis and treatment
Abstract
In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of
greater clinical significance than previously believed, the Polish Society of Endocrinology has recently published recommendations on the
diagnosis and management of PA. Due to the fact that the currently available tests cannot be considered the gold standard in the diagnosis
of PA and the discrepancies in the results of determination of aldosterone levels and plasma renin activity (PRA) are considerable the
authors of this document do not provide strict cutoff values, leaving the interpretation of results to clinicians. This paper, which focuses
on screening and confirmatory tests and on the aetiological diagnosis and treatment of PA, is based on the experience of the Department
of Endocrinology, Diabetes and Internal Diseases, Medical University in Bialystok, Poland, but it also takes into account other points of
view presented in papers published in the past few years. (Endokrynol Pol 2012; 63 (education supplement II) 1–14)
Keywords: plasma aldosterone concentrationplasma renin activityaldosterone-renin ratioconfirmatory tests