Corneal edema recovery after phacoemulsification in type 2 diabetic versus non-diabetic patients
, 2, 3, 4, 5
Abstract
Background. Ultrasound energy during phacoemul-sification can cause mechanical trauma to corneal endothelium which leads to prolonged postoperative recovery. Several studies have reported conflicting results of corneal changes after phacoemuslification in diabetic versus non-diabetic patients. We aimed to assess corneal edema recovery and compare best corrected visual acuity (BCVA) after phacoemulsification in patients with diabetes mellitus type 2 versus patients without type 2 diabetes.
Methods. The study included type 2 diabetic and non-diabetic patients who underwent phacoemulsification between November 2018 and May 2019. Assessments of corneal edema recovery were done preoperative and on postoperative day 1, after 1 week and after two months. BCVA were taken preoperative and postoperative after 1 week and 2 months after the surgery. Results. There was no significant difference between groups in corneal status on check-up examinations. Corneal edema recovery was equal between the pa-tients with and without diabetes mellitus type 2. No significant difference in mean BCVA was observed between the studied groups after the operation.
Conclusion. Considering the use of modern technology in cataract surgery, there was no difference in postoperative results between non-diabetic and type 2 diabetic patients.
Keywords: cataractphacoemulsificationcorneal edemadiabetes mellitusvisual acuity
References
- Saeedi P, Salpea P, Karuranga S, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9 edition. Diabetes Res Clin Pract. 2019; 157: 107843.
- Javadi MA, Zarei-Ghanavati S. Cataracts in diabetic patients: a review article. J Ophthalmic Vis Res. 2008; 3(1): 52–65.
- Tang Y, Chen X, Zhang X, et al. Clinical evaluation of corneal changes after phacoemulsification in diabetic and non-diabetic cataract patients, a systematic review and meta-analysis. Sci Rep. 2017; 7(1): 14128.
- Chylack L. The Lens Opacities Classification System III. Archives of Ophthalmology. 1993; 111(6): 831.
- Use of a grading system in the evaluation of complications in a randomised controlled trial on cataract surgery. Oxford Cataract Treatment and Evaluation Team (OCTET). Br J Ophthalmol. 1986; 70(6): 411–414.
- Shih KCo, Lam KSL, Tong L. A systematic review on the impact of diabetes mellitus on the ocular surface. Nutr Diabetes. 2017; 7(3): e251.
- Kirkman MS, Briscoe VJ, Clark N, et al. Diabetes in older adults. Diabetes Care. 2012; 35(12): 2650–2664.
- Thomas RL, Halim S, Gurudas S, et al. IDF Diabetes Atlas: A review of studies utilising retinal photography on the global prevalence of diabetes related retinopathy between 2015 and 2018. Diabetes Res Clin Pract. 2019; 157: 107840.
- Kelkar A, Kelkar J, Mehta H, et al. Cataract surgery in diabetes mellitus: A systematic review. Indian J Ophthalmol. 2018; 66(10): 1401–1410.
- Hugod M, Storr-Paulsen A, Norregaard JC, et al. Corneal endothelial cell changes associated with cataract surgery in patients with type 2 diabetes mellitus. Cornea. 2011; 30(7): 749–753.
- Kausar A, Farooq S, Akhter W, et al. Transient corneal edema after phacoemulsification. J Coll Physicians Surg Pak. 2015; 25(7): 505–509.
- Al-Sharkawy H. Corneal endothelial changes in type 2 diabetes mellitus before and after cataract surgery. Journal of the Egyptian Ophthalmological Society. 2015; 108(2): 79.
- Budiman B. Comparison of endothelial cell density, morphological changes and central corneal thickness after phacoemulsification between diabetic and non-diabetic patients. The Open Ophthalmology Journal. 2020; 14(1): 15–20.
- Tsaousis KT, Panagiotou DZ, Kostopoulou E, et al. Corneal oedema after phacoemulsification in the early postoperative period: A qualitative comparative case-control study between diabetics and non-diabetics. Ann Med Surg (Lond). 2016; 5: 67–71.
- Shakya K, Pokharel S, Karki KJD, et al. Corneal edema after phacoemulsification surgery in patients with type II diabetes mellitus. Nepal J Ophthalmol. 2013; 5(2): 230–234.
- Khalid M, Hanif MK, Islam QUl, et al. Change in corneal endothelial cell density after phacoemulsification in patients with type II diabetes mellitus. Pak J Med Sci. 2019; 35(5): 1366–1369.
- He Xu, Diakonis VF, Alavi Y, et al. Endothelial cell loss in diabetic and nondiabetic eyes after cataract surgery. Cornea. 2017; 36(8): 948–951.
- Bamdad S, Bolkheir A, Sedaghat MR, et al. Changes in corneal thickness and corneal endothelial cell density after phacoemulsification cataract surgery: a double-blind randomized trial. Electron Physician. 2018; 10(4): 6616–6623.
- El-Agamy A, Alsubaie S. Corneal endothelium and central corneal thickness changes in type 2 diabetes mellitus. Clin Ophthalmol. 2017; 11: 481–486.