open access

Vol 8, No 6 (2019)
REVIEW ARTICLES
Published online: 2020-01-23
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Muscle cramps — a mini review of possible causes and treatment options available with a special emphasis on diabetics — a narrative review

Sayak Roy
DOI: 10.5603/DK.2019.0029
·
Clinical Diabetology 2019;8(6):310-317.

open access

Vol 8, No 6 (2019)
REVIEW ARTICLES
Published online: 2020-01-23

Abstract

Muscle cramps are characterized by sudden, painful involuntary contraction of the muscles. The cramps sometimes become disabling and the prevalence is more in the elderly. The etiology of the cramps are diverse and some time the cramps are idiopathic. There are many underlying pathophysiological disorders like hypocalcemia, hypomagnesemia, hypothyroidism, and hepatorenal dysfunction which causes muscle cramp. Similarly, diabetes mellitus results in muscle cramps due to electrolytic imbalance, hypoglycemia, peripheral arterial insufficiency, and neuropathies. Persistent muscle pain in diabetic patients degrades the quality of life of those patients. Although the pathophysiology and etiology of the muscle cramp are understood to some extent, the same is less explored from diabetes mellitus perspective. Hence the objective of this review is to explore the underlying factors responsible for muscle cramps in diabetes so that proper strategy for pharmacotherapy can be made to manage this condition.

Abstract

Muscle cramps are characterized by sudden, painful involuntary contraction of the muscles. The cramps sometimes become disabling and the prevalence is more in the elderly. The etiology of the cramps are diverse and some time the cramps are idiopathic. There are many underlying pathophysiological disorders like hypocalcemia, hypomagnesemia, hypothyroidism, and hepatorenal dysfunction which causes muscle cramp. Similarly, diabetes mellitus results in muscle cramps due to electrolytic imbalance, hypoglycemia, peripheral arterial insufficiency, and neuropathies. Persistent muscle pain in diabetic patients degrades the quality of life of those patients. Although the pathophysiology and etiology of the muscle cramp are understood to some extent, the same is less explored from diabetes mellitus perspective. Hence the objective of this review is to explore the underlying factors responsible for muscle cramps in diabetes so that proper strategy for pharmacotherapy can be made to manage this condition.

Get Citation

Keywords

muscle cramps, diabetes mellitus, hypocalcemia, hypomagnesemia

About this article
Title

Muscle cramps — a mini review of possible causes and treatment options available with a special emphasis on diabetics — a narrative review

Journal

Clinical Diabetology

Issue

Vol 8, No 6 (2019)

Pages

310-317

Published online

2020-01-23

DOI

10.5603/DK.2019.0029

Bibliographic record

Clinical Diabetology 2019;8(6):310-317.

Keywords

muscle cramps
diabetes mellitus
hypocalcemia
hypomagnesemia

Authors

Sayak Roy

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