open access

Vol 5, No 4 (2016)
Review
Published online: 2016-11-03
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Insulin therapy and lipoproteins in patients with type 1 diabetes

Aleksandra Cieluch, Aleksandra Uruska, Agata Grzelka, Dorota Zozulińska-Ziółkiewicz
DOI: 10.5603/DK.2016.0019
·
Clinical Diabetology 2016;5(4):111-116.

open access

Vol 5, No 4 (2016)
Review
Published online: 2016-11-03

Abstract

Knowledge on HDL cholesterol has been extended, however, there are still unknown facts, especially concerning HDL cholesterol, type 1 diabetes mellitus and insulin therapy. It is known that HDL is responsible for the transport of cholesterol to the liver. It is called the “good cholesterol” due to its advantageous properties. HDL cholesterol reduces cardiovascular risk by its anti-inflammatory, antioxidant, profibrinolytic and antithrombotic effects. The influence of HDL on the incidence of chronic complications of type 1 diabetes has not been yet fully understood. The researchers observed an increase in HDL cholesterol level after initiation of insulin therapy. Significant is the fact that insulin affects lipoprotein metabolism in type 1 diabetes, as it is the treatment of choice in this group of patients.

Abstract

Knowledge on HDL cholesterol has been extended, however, there are still unknown facts, especially concerning HDL cholesterol, type 1 diabetes mellitus and insulin therapy. It is known that HDL is responsible for the transport of cholesterol to the liver. It is called the “good cholesterol” due to its advantageous properties. HDL cholesterol reduces cardiovascular risk by its anti-inflammatory, antioxidant, profibrinolytic and antithrombotic effects. The influence of HDL on the incidence of chronic complications of type 1 diabetes has not been yet fully understood. The researchers observed an increase in HDL cholesterol level after initiation of insulin therapy. Significant is the fact that insulin affects lipoprotein metabolism in type 1 diabetes, as it is the treatment of choice in this group of patients.

Get Citation

Keywords

lipoproteins, type 1 diabetes, HDL cholesterol, insulin therapy, chronic diabetic complications

About this article
Title

Insulin therapy and lipoproteins in patients with type 1 diabetes

Journal

Clinical Diabetology

Issue

Vol 5, No 4 (2016)

Pages

111-116

Published online

2016-11-03

DOI

10.5603/DK.2016.0019

Bibliographic record

Clinical Diabetology 2016;5(4):111-116.

Keywords

lipoproteins
type 1 diabetes
HDL cholesterol
insulin therapy
chronic diabetic complications

Authors

Aleksandra Cieluch
Aleksandra Uruska
Agata Grzelka
Dorota Zozulińska-Ziółkiewicz

References (23)
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