open access

Vol 1, No 1 (2000): Practical Diabetology
Original articles (translated)
Published online: 2000-09-26
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Frequency of Liver Disease in Type 2 Diabetic Patients Treated With Oral Antidiabetic Agents

Susan S. Jick, Monica Stender, Marian W. Myers
Diabetologia Praktyczna 2000;1(1):75-82.

open access

Vol 1, No 1 (2000): Practical Diabetology
Original articles (translated)
Published online: 2000-09-26

Abstract

OBJECTIVE. We evaluated liver disease in conventionally treated type 2 diabetic patients to provide a reference against which reports of liver disease related to novel oral antidiabetic treatments could be compared.
RESEARCH DESIGN AND METHODS. In this follow-up study, patients with type 2 diabetes who were treated with oral antidiabetic agents were identified from the U.K.-based General Practice Research Database and were followed to determine whether they developed liver disease. The specific types and etiologies of liver disorders were determined. Incidence rates were calculated based on the accumulated exposure time to oral antidiabetic agents.
RESULTS. Among 44,406 type 2 diabetic patients, 605 had a computer diagnosis of liver disease with an incidence rate of 53.2/10,000 person-years (95% CI 49.2–57.6). Of the 605 subjects, 186 had nonsymp

Abstract

OBJECTIVE. We evaluated liver disease in conventionally treated type 2 diabetic patients to provide a reference against which reports of liver disease related to novel oral antidiabetic treatments could be compared.
RESEARCH DESIGN AND METHODS. In this follow-up study, patients with type 2 diabetes who were treated with oral antidiabetic agents were identified from the U.K.-based General Practice Research Database and were followed to determine whether they developed liver disease. The specific types and etiologies of liver disorders were determined. Incidence rates were calculated based on the accumulated exposure time to oral antidiabetic agents.
RESULTS. Among 44,406 type 2 diabetic patients, 605 had a computer diagnosis of liver disease with an incidence rate of 53.2/10,000 person-years (95% CI 49.2–57.6). Of the 605 subjects, 186 had nonsymp
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About this article
Title

Frequency of Liver Disease in Type 2 Diabetic Patients Treated With Oral Antidiabetic Agents

Journal

Clinical Diabetology

Issue

Vol 1, No 1 (2000): Practical Diabetology

Pages

75-82

Published online

2000-09-26

Bibliographic record

Diabetologia Praktyczna 2000;1(1):75-82.

Authors

Susan S. Jick
Monica Stender
Marian W. Myers

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