open access

Vol 3, No 2 (2002): Practical Diabetology
Original articles (translated)
Published online: 2002-05-13
Get Citation

Association of Chlamydia pneumoniae infection with diabetic nephropathy

Masao Kanauchi, Takahiro Kawano, Kazuhiro Dohi
Diabetologia Praktyczna 2002;3(2):91-94.

open access

Vol 3, No 2 (2002): Practical Diabetology
Original articles (translated)
Published online: 2002-05-13

Abstract

We evaluated the association of Chlamydia pneumoniae (CP) infection with progression of diabetic nephropathy. Type 2 diabetic patients (60) were divided into two groups, those with incipient nephropathy and those with advanced nephropathy, based on the severity of diffuse glomerular lesions using Gellman’s criteria. Type 2 (34) diabetic patients without nephropathy (normoalbuminuria) and 59 nondiabetics served as control groups. Serum IgG- -antibody against CP was measured using ELISA. CP antibody was detected in 45.8% of nondiabetic controls, in 47.1% of diabetic patients without nephropathy, in 52.6% of diabetic patients with incipient nephropathy, and 78% of diabetic patients with advanced nephropathy. There was 4.22-fold increase in the risk of advanced nephropathy associated with the presence of CP antibody. Our findings indicate an association between chronic CP infection and advanced diabetic nephropathy.

Abstract

We evaluated the association of Chlamydia pneumoniae (CP) infection with progression of diabetic nephropathy. Type 2 diabetic patients (60) were divided into two groups, those with incipient nephropathy and those with advanced nephropathy, based on the severity of diffuse glomerular lesions using Gellman’s criteria. Type 2 (34) diabetic patients without nephropathy (normoalbuminuria) and 59 nondiabetics served as control groups. Serum IgG- -antibody against CP was measured using ELISA. CP antibody was detected in 45.8% of nondiabetic controls, in 47.1% of diabetic patients without nephropathy, in 52.6% of diabetic patients with incipient nephropathy, and 78% of diabetic patients with advanced nephropathy. There was 4.22-fold increase in the risk of advanced nephropathy associated with the presence of CP antibody. Our findings indicate an association between chronic CP infection and advanced diabetic nephropathy.
Get Citation

Keywords

Chlamydia pneumoniae; diabetic nephropathy; renal biopsy

About this article
Title

Association of Chlamydia pneumoniae infection with diabetic nephropathy

Journal

Clinical Diabetology

Issue

Vol 3, No 2 (2002): Practical Diabetology

Pages

91-94

Published online

2002-05-13

Bibliographic record

Diabetologia Praktyczna 2002;3(2):91-94.

Keywords

Chlamydia pneumoniae
diabetic nephropathy
renal biopsy

Authors

Masao Kanauchi
Takahiro Kawano
Kazuhiro Dohi

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

 

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl