open access

Vol 5, No 1 (2004): Practical Diabetology
Review articles (submitted)
Published online: 2004-02-02
Get Citation

Hormonal replacement therapy in postmenopausal diabetic women

Andrzej Milewicz, Diana Jędrzejuk
Diabetologia Praktyczna 2004;5(1):41-44.

open access

Vol 5, No 1 (2004): Practical Diabetology
Review articles (submitted)
Published online: 2004-02-02

Abstract

In postmenopausal women due to the lack of the sex hormones occur the metabolic changes. Visceral obesity, insulin resistance, dyslipidemia, hypertension are the risk factors for cardiovascular diseases. These factors create the menopausal metabolic syndrome (syndrome X or syndrome W). After menopause the number of women with diabetes mellitus is growing up. Menopause and diabetes cause to higher mortality of cardiovascular diseases. Hormonal replacement therapy in diabetic postmenopausal women should be “tailored”. Diabetic postmenopausal women often suffer from endometrial carcinoma, fatty liver, cholecystolithiasis, hypertension, hipertriglycerydemia, insulin resistance. Hormone replacement therapy should be provided transdermal to avoid the above concomitant illnesses. The progestagen which should be prescribed by intact uterus should bind only progesterone’s receptor (not glycocorticosteroid’s receptor).

Abstract

In postmenopausal women due to the lack of the sex hormones occur the metabolic changes. Visceral obesity, insulin resistance, dyslipidemia, hypertension are the risk factors for cardiovascular diseases. These factors create the menopausal metabolic syndrome (syndrome X or syndrome W). After menopause the number of women with diabetes mellitus is growing up. Menopause and diabetes cause to higher mortality of cardiovascular diseases. Hormonal replacement therapy in diabetic postmenopausal women should be “tailored”. Diabetic postmenopausal women often suffer from endometrial carcinoma, fatty liver, cholecystolithiasis, hypertension, hipertriglycerydemia, insulin resistance. Hormone replacement therapy should be provided transdermal to avoid the above concomitant illnesses. The progestagen which should be prescribed by intact uterus should bind only progesterone’s receptor (not glycocorticosteroid’s receptor).
Get Citation

Keywords

diabetes mellitus type 2; hormonal replacement therapy; menopausal syndrome

About this article
Title

Hormonal replacement therapy in postmenopausal diabetic women

Journal

Clinical Diabetology

Issue

Vol 5, No 1 (2004): Practical Diabetology

Pages

41-44

Published online

2004-02-02

Bibliographic record

Diabetologia Praktyczna 2004;5(1):41-44.

Keywords

diabetes mellitus type 2
hormonal replacement therapy
menopausal syndrome

Authors

Andrzej Milewicz
Diana Jędrzejuk

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