open access

Vol 5, No 3 (2004): Practical Diabetology
Original articles (submitted)
Published online: 2004-05-20
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The prevalence of the components of metabolic syndrome among obese patients

Katarzyna Cyganek, Jacek Sieradzki
Diabetologia Praktyczna 2004;5(3):123-129.

open access

Vol 5, No 3 (2004): Practical Diabetology
Original articles (submitted)
Published online: 2004-05-20

Abstract

INTRODUCTION. Metabolic activity of fat tissue underlines the metabolic syndrome witch is clearly associated with increased risk for coronary heart diseases. The aim of the study was to asses the prevalence of components of metabolic syndrome among obese patients.
MATERIAL AND METHODS. We examined 216 patients with obesity. We assessed measurements: weight, height, waist and hip circumference, free fat mass by using bioelectric impedance spectroscopy (BODYSTAT 1500), blood pressure and lipid profile, plasma glucose and insulin level fasting and 2 hours post loaded 75 g of glucose, insulin resistance (IR) was quantified using the homeostasis model assessment (HOMA). Metabolic syndrome was diagnosed using the NCEP ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria.
RESULTS. Mean BMI was 42,3 (± 7,4) kg/m2. Metabolic syndrome was present among 131 (60,6%) individuals, and 70 (32,4%) meet 3 features, 53 (24,5%) with 4 and 8 (3,7%) with 5. Glucose abnormalities was higher in participants with metabolic syndrome (MS) among 560 (42,7%) patients vs. 7 (8,2%) without metabolic syndrome (WMS). The group with MS had statistically higher weight [117,3 (± 22,8) vs. 107,1 (± 19,5) kg; p = 0,001], waist circumference [120,7 (± 15,2) vs. 113,5 (± 14,9) cm; p = 0,001] and free fat mass [54,2 (± 15,3) vs. 48,9 (± 14,5) kg; p = 0,006)] also had the highest fasting levels of glucose [5,7 (± 1,7) vs. 4,8 (± 0,6) mmol/l; p = 0,00002], insulin [21,4 (± 17,1) vs. 16,0 (± 13,0) mIU/ml; p = 0,06] and HOMA-IR [5,7 (± 5,6) vs. 3,7 (± 3,1); p = 0,007]. Patients with SM had statistically higher level of total cholesterol [5,5 (± 0,9) vs. 5,1 (± 1,0) mmol/l; p = 0,004], triglycerides [2,1 (± 0,9) vs. 1,3 (± 0,5) mmol/l; p = 0,00000] and lower level of HDL-cholesterol [1,2 (± 0,5) vs. 1,4 (± 0,5) mmol/l; p = 0,001]. Systolic blood pressure was higher in MS group than WMS [141,9 (± 21,4) vs. 133,2 (± 22,0) mm Hg; p = 0,004].
CONCLUSIONS. The prevalence of metabolic abnormalities is very high among patients with morbid obesity. The number of components of metabolic syndrome increase with weight and waist circumference.

Abstract

INTRODUCTION. Metabolic activity of fat tissue underlines the metabolic syndrome witch is clearly associated with increased risk for coronary heart diseases. The aim of the study was to asses the prevalence of components of metabolic syndrome among obese patients.
MATERIAL AND METHODS. We examined 216 patients with obesity. We assessed measurements: weight, height, waist and hip circumference, free fat mass by using bioelectric impedance spectroscopy (BODYSTAT 1500), blood pressure and lipid profile, plasma glucose and insulin level fasting and 2 hours post loaded 75 g of glucose, insulin resistance (IR) was quantified using the homeostasis model assessment (HOMA). Metabolic syndrome was diagnosed using the NCEP ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria.
RESULTS. Mean BMI was 42,3 (± 7,4) kg/m2. Metabolic syndrome was present among 131 (60,6%) individuals, and 70 (32,4%) meet 3 features, 53 (24,5%) with 4 and 8 (3,7%) with 5. Glucose abnormalities was higher in participants with metabolic syndrome (MS) among 560 (42,7%) patients vs. 7 (8,2%) without metabolic syndrome (WMS). The group with MS had statistically higher weight [117,3 (± 22,8) vs. 107,1 (± 19,5) kg; p = 0,001], waist circumference [120,7 (± 15,2) vs. 113,5 (± 14,9) cm; p = 0,001] and free fat mass [54,2 (± 15,3) vs. 48,9 (± 14,5) kg; p = 0,006)] also had the highest fasting levels of glucose [5,7 (± 1,7) vs. 4,8 (± 0,6) mmol/l; p = 0,00002], insulin [21,4 (± 17,1) vs. 16,0 (± 13,0) mIU/ml; p = 0,06] and HOMA-IR [5,7 (± 5,6) vs. 3,7 (± 3,1); p = 0,007]. Patients with SM had statistically higher level of total cholesterol [5,5 (± 0,9) vs. 5,1 (± 1,0) mmol/l; p = 0,004], triglycerides [2,1 (± 0,9) vs. 1,3 (± 0,5) mmol/l; p = 0,00000] and lower level of HDL-cholesterol [1,2 (± 0,5) vs. 1,4 (± 0,5) mmol/l; p = 0,001]. Systolic blood pressure was higher in MS group than WMS [141,9 (± 21,4) vs. 133,2 (± 22,0) mm Hg; p = 0,004].
CONCLUSIONS. The prevalence of metabolic abnormalities is very high among patients with morbid obesity. The number of components of metabolic syndrome increase with weight and waist circumference.
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Keywords

metabolic syndrome; obesity; insulin resistance; diabetes; fat tissue; adiposities

About this article
Title

The prevalence of the components of metabolic syndrome among obese patients

Journal

Clinical Diabetology

Issue

Vol 5, No 3 (2004): Practical Diabetology

Pages

123-129

Published online

2004-05-20

Bibliographic record

Diabetologia Praktyczna 2004;5(3):123-129.

Keywords

metabolic syndrome
obesity
insulin resistance
diabetes
fat tissue
adiposities

Authors

Katarzyna Cyganek
Jacek Sieradzki

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