INTRODUCTION. Overweight or obesity effect over 50% of population in developed countries. The aim of the study was to evaluate the effect of selected factors on lipid disorders in obese patients.
MATERIAL AND METHODS. A group of 97 overweight and obese patients, aged 18-55, was analyzed. Patients taking cigarettes, medicaments or suffering from diseases influencing lipid metabolism were excluded. BMI, levels of TC-cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides (TG) were estimated depending on age, gender, systolic blood pressure, diastolic blood pressure and the carbohydrate metabolism disorders.
RESULTS. BMI was significantly higher in women compared to men in the analyzed population (40,6 ± 9,2 vs. 35,7 ± 6,7 kg/m², p < 0,01). There were no important differences in lipid metabolism parameters between the obese and highly obese patients (BMI > 40 kg/m²). Significantly higher TG values were observed in the people aged 35-55 in comparison to the younger ones - 18-34 years old, (281,6 ± 336,1 vs. 169,2 ± 118,1 mg/dl; p < 0,05) and also in the diabetic patients compared to the people without carbohydrate metabolism disorders (309,9 ± 310,9 vs. 222,7 ± 309,9; p < 0,01). The other lipid metabolism parameters did not differ between the analyzed groups. Significantly higher BMI was observed in patients with the diastolic blood pressure > 90 mm Hg in comparison to the patients with the diastolic blood pressure < 90 mm Hg (42,1 ± 8,4 vs. 37,9 ± 8,7 kg/m²; p < 0,05).
CONCLUSIONS. In the studied group, the level of obesity, gender and arterial blood pressure do not influence lipid metabolism in overweight patients up to 55 years old. Only the TG level depended on age. Whereas the level of obesity positively correlates with diastolic blood pressure.