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Hypoglycaemic episodes in patients with diabetes in course of liver cirrhosis
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Abstract
MATERIAL AND METHODS. 18 patients with diabetes in course of liver cirrhosis and 18 type 2 diabetic patients (control group) were enrolled into the study. All patients were treated with insulin. During 72 hours glucose values with CGMS was measured, insulin treatment was not modified. The state of hypoglycemia assumed as glucose value < 60 mg/dl. Duration and number of hypoglycaemic events, including symptom-free hypoglycaemic episodes were analyzed in both groups.
RESULTS. Mean number of hypoglycaemic events detected with CGMS for three days was higher for patients with hepatogenous diabetes than for type 2 patients (p = 0.02). Mean number of symptom-free hypoglycaemic events detected with CGMS was statistically similar in both groups (NS). Mean duration of hypoglycaemic episodes, including symptom-free hypoglycaemic episodes was similar in both groups (NS).
CONCLUSIONS. It was concluded, that hepatogenic diabetes is associated with essentially higher number of hypoglycaemic events than type 2 diabetes. CGMS is useful in diabetic patients with liver cirrhosis for hypoglycaemic episodes detection.
Abstract
MATERIAL AND METHODS. 18 patients with diabetes in course of liver cirrhosis and 18 type 2 diabetic patients (control group) were enrolled into the study. All patients were treated with insulin. During 72 hours glucose values with CGMS was measured, insulin treatment was not modified. The state of hypoglycemia assumed as glucose value < 60 mg/dl. Duration and number of hypoglycaemic events, including symptom-free hypoglycaemic episodes were analyzed in both groups.
RESULTS. Mean number of hypoglycaemic events detected with CGMS for three days was higher for patients with hepatogenous diabetes than for type 2 patients (p = 0.02). Mean number of symptom-free hypoglycaemic events detected with CGMS was statistically similar in both groups (NS). Mean duration of hypoglycaemic episodes, including symptom-free hypoglycaemic episodes was similar in both groups (NS).
CONCLUSIONS. It was concluded, that hepatogenic diabetes is associated with essentially higher number of hypoglycaemic events than type 2 diabetes. CGMS is useful in diabetic patients with liver cirrhosis for hypoglycaemic episodes detection.
Keywords
diabetes mellitus; cirrhosis hepatis; hypoglycaemia; continuous glucose monitoring system
About this articleTitle
Hypoglycaemic episodes in patients with diabetes in course of liver cirrhosis
Journal
Issue
Vol 6, No 6 (2005): Practical Diabetology
Article type
Research paper
Pages
307-311
Published online
2005-11-03
Page views
500
Article views/downloads
2159
DOI
10.5603/cd.8589
Bibliographic record
Diabetologia Praktyczna 2005;6(6):307-311.
Keywords
diabetes mellitus
cirrhosis hepatis
hypoglycaemia
continuous glucose monitoring system
Authors
Leszek Markuszewski
Michał Możdżan
Michał Barański
Jan Ruxer