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Vol 7, No 5 (2006): Practical Diabetology
Review article
Submitted: 2012-01-02
Published online: 2006-09-28
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Practical approach to the intensification of insulin therapy in type 2 diabetes mellitus - the algorithm of switch from biphasic human insulin to biphasic aspart insulin

Maciej T. Małecki, Teresa Koblik, Bogumił Wolnik, Jacek Sieradzki
Diabetologia Praktyczna 2006;7(5):295-299.

open access

Vol 7, No 5 (2006): Practical Diabetology
Review articles (submitted)
Submitted: 2012-01-02
Published online: 2006-09-28

Abstract

In recent years, the need of intensifying and improving metabolic control in type 2 diabetes is becoming more and more important. The majority of insulin treated type 2 patients in Poland receives human insulin premixes that in many cases are not sufficient to prevent diabetes complications, particularly macroangiopathy as a consequence of inadequate postprandial glycaemic control. Biphasic insulin analogues seem to be a good tool to improve diabetes control in those patients, they are convenient to administer and provide appropriate control the postprandial glycaemia peaks without compromising hypoglycaemia risk. This paper contains practical considerations and guidelines based on authors clinical experience that could be helpful in safe switching type 2 patients from human insulin premixes to biphasic insulin aspart preparations.

Abstract

In recent years, the need of intensifying and improving metabolic control in type 2 diabetes is becoming more and more important. The majority of insulin treated type 2 patients in Poland receives human insulin premixes that in many cases are not sufficient to prevent diabetes complications, particularly macroangiopathy as a consequence of inadequate postprandial glycaemic control. Biphasic insulin analogues seem to be a good tool to improve diabetes control in those patients, they are convenient to administer and provide appropriate control the postprandial glycaemia peaks without compromising hypoglycaemia risk. This paper contains practical considerations and guidelines based on authors clinical experience that could be helpful in safe switching type 2 patients from human insulin premixes to biphasic insulin aspart preparations.

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Keywords

type 2 diabetes; human insulin; aspart insulin; premixed insulins

About this article
Title

Practical approach to the intensification of insulin therapy in type 2 diabetes mellitus - the algorithm of switch from biphasic human insulin to biphasic aspart insulin

Journal

Clinical Diabetology

Issue

Vol 7, No 5 (2006): Practical Diabetology

Article type

Review article

Pages

295-299

Published online

2006-09-28

Page views

449

Article views/downloads

1846

Bibliographic record

Diabetologia Praktyczna 2006;7(5):295-299.

Keywords

type 2 diabetes
human insulin
aspart insulin
premixed insulins

Authors

Maciej T. Małecki
Teresa Koblik
Bogumił Wolnik
Jacek Sieradzki

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