open access

Vol 7, No 6 (2006): Practical Diabetology
Original articles (submitted)
Published online: 2006-10-18
Get Citation

The incidence of impaired carbohydrate metabolism in the examined group of subjects with risk factors

Zofia Ruprecht, Anna Kamińska, Maria Skibicka, Roman Junik
Diabetologia Praktyczna 2006;7(6):374-381.

open access

Vol 7, No 6 (2006): Practical Diabetology
Original articles (submitted)
Published online: 2006-10-18

Abstract

INTRODUCTION. The aim of this study was to evaluate of the incidence of impaired carbohydrate metabolism in the group of subjects with risk factors of type 2 diabetes mellitus (DM).
MATERIAL AND METHODS. We studied 330 subjects and 201 of them were required to further investigations. This group consisted of 125 females (62%) and 76 males (38%) (mean age 58.5 ± 12.45 years, BMI 35.5 ± 4.59 kg/m2) who felt healthy but had risk factors of DM.
The study was conducted in the Department of Endocrinology and Diabetology in cooperation with 4 general practitioners. In the first phase of the study subjects were asked to fill in a questionnaire in order to identify risk factors of DM. Capillary blood glucose was estimated by use of a glucometer. Subjects with incidental blood glucose above 6.1 mmol/l progressed to the second phase of the study - an estimation of FPG and, if required, OGTT.
RESULTS. In 70 of 201 examined subjects (35%) we found: in 12 impaired fasting glucose (IFG), in 28 impaired glucose tolerance (IGT), in 30 DM. Subjects with IFG, IGT, DM were different from subjects without impaired carbohydrate metabolism in relation to: age (64.8 ± 10.2 vs. 57.0 ± 12.7 years - p < 0.001), BMI (30.1 ± 4.8 vs. 27.4 ± 4.2 kg/m2 -
p < 0.001), number of risk factors (3.8 ± 1.1 vs. 3.2 ± 1.5 - p < 0.01), systolic blood pressure (144.1 ± 22.3 vs. 135.5 ± 20 mm Hg - p < 0.01). There was higher incidence of risk factors in the group with impaired carbohydrate metabolism in comparision to the group without abnormalities in carbohydrate metabolism: age ≥ 45 years - 98.6% vs. 86.2%, BMI > 25 kg/m2 - 84.2% vs. 68.7%, arterial hypertension - 68.6% vs. 48%, dyslipidemia - 57.8% vs. 50%, the history of IGT 8.9% vs. 7.1%, the history of cardiovascular incident 18.8% vs. 14.8%.
CONCLUSIONS. Subjects with impaired carbohydrate metabolism were older, had higher weight and more risk factors of DM in comparision to subjects without abnormalities in carbohydrate metabolism. The most frequent risk factors of DM in the examined group were, apart from age, excessive body mass, arterial hypertension and dyslipidemia.

Abstract

INTRODUCTION. The aim of this study was to evaluate of the incidence of impaired carbohydrate metabolism in the group of subjects with risk factors of type 2 diabetes mellitus (DM).
MATERIAL AND METHODS. We studied 330 subjects and 201 of them were required to further investigations. This group consisted of 125 females (62%) and 76 males (38%) (mean age 58.5 ± 12.45 years, BMI 35.5 ± 4.59 kg/m2) who felt healthy but had risk factors of DM.
The study was conducted in the Department of Endocrinology and Diabetology in cooperation with 4 general practitioners. In the first phase of the study subjects were asked to fill in a questionnaire in order to identify risk factors of DM. Capillary blood glucose was estimated by use of a glucometer. Subjects with incidental blood glucose above 6.1 mmol/l progressed to the second phase of the study - an estimation of FPG and, if required, OGTT.
RESULTS. In 70 of 201 examined subjects (35%) we found: in 12 impaired fasting glucose (IFG), in 28 impaired glucose tolerance (IGT), in 30 DM. Subjects with IFG, IGT, DM were different from subjects without impaired carbohydrate metabolism in relation to: age (64.8 ± 10.2 vs. 57.0 ± 12.7 years - p < 0.001), BMI (30.1 ± 4.8 vs. 27.4 ± 4.2 kg/m2 -
p < 0.001), number of risk factors (3.8 ± 1.1 vs. 3.2 ± 1.5 - p < 0.01), systolic blood pressure (144.1 ± 22.3 vs. 135.5 ± 20 mm Hg - p < 0.01). There was higher incidence of risk factors in the group with impaired carbohydrate metabolism in comparision to the group without abnormalities in carbohydrate metabolism: age ≥ 45 years - 98.6% vs. 86.2%, BMI > 25 kg/m2 - 84.2% vs. 68.7%, arterial hypertension - 68.6% vs. 48%, dyslipidemia - 57.8% vs. 50%, the history of IGT 8.9% vs. 7.1%, the history of cardiovascular incident 18.8% vs. 14.8%.
CONCLUSIONS. Subjects with impaired carbohydrate metabolism were older, had higher weight and more risk factors of DM in comparision to subjects without abnormalities in carbohydrate metabolism. The most frequent risk factors of DM in the examined group were, apart from age, excessive body mass, arterial hypertension and dyslipidemia.
Get Citation

Keywords

detection of diabetes; screening; risk factors

About this article
Title

The incidence of impaired carbohydrate metabolism in the examined group of subjects with risk factors

Journal

Clinical Diabetology

Issue

Vol 7, No 6 (2006): Practical Diabetology

Pages

374-381

Published online

2006-10-18

Bibliographic record

Diabetologia Praktyczna 2006;7(6):374-381.

Keywords

detection of diabetes
screening
risk factors

Authors

Zofia Ruprecht
Anna Kamińska
Maria Skibicka
Roman Junik

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

 

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl