Vol 7, No 6 (2006): Practical Diabetology
Research paper
Published online: 2006-10-18
Influence of temporary glycemic levels on gastric mioelectrical function in electrogastrografical examination in type 1 diabetics
Diabetologia Praktyczna 2006;7(6):353-365.
Abstract
INTRODUCTION. Electrogastrography have demonstrated a significant influence of glycaemia on the electrogastrographic values. Until now, however, the relationship has not been exactly expressed. One of
the aims of this study was estimation of coincidence of glicemia and myoelectrical activity of stomach
between patients with diabetes type 1.
MATERIAL AND METHODS. The study covered 106 patients with type 1 diabetes. Gastric myoelectric activity was recorded with a Digitraper EGG OS unit, release 03.00.
RESULTS. A statistically significant difference of mean glycaemia values (G0, GI, GP, G30, G60) during the electrogastrographic record between group C1 (deemed to represent a normal electrogastrographic record) and groups C2, C3, C4, where, depending on the percentage distribution of preprandial and postprandial frequencies, patients electrogastrographic records did not comply with the normative criteria. Significant differences between mean glycaemia values were found in the group with glicated haemoglobin values above 7.5%. Although group C3 demonstrated much higher mean glycaemia values in the range HbA1c > 7.5% (by a factor of 1.67), in group C2 the difference of mean glycaemia values in both ranges of glicated haemoglobin values was 1.09. It proves that the statistically significant difference of mean glycaemia values between group C1 and groups C2, C3, C4 for glicated haemoglobin above 7.5% was not only due to differences of mean glycaemia values depending on the haemoglobin value. In other words, the statistically significant difference in mean values between the groups does not only arise out of the fact that patients from the glicated haemoglobin range in excess of 7.5% represent a group of patients with higher mean glycaemia values. Another proof that there is no direct relationship is the insignificance of the differences of mean glycaemia values between groups C2 and C3, C2 and C4, C3 and C4 irrespective of the glicated haemoglobin value.
CONCLUSION. Thus, it seems that momentary glycaemia values during the electrogastrographic record do not demonstrate any effect on the electrogastrographic parameters when its values are correct. On the other hand, such effect is visible with an incorrect electrogastrographic record, and is seen more clearly when the glicated haemoglobin value is considered.
MATERIAL AND METHODS. The study covered 106 patients with type 1 diabetes. Gastric myoelectric activity was recorded with a Digitraper EGG OS unit, release 03.00.
RESULTS. A statistically significant difference of mean glycaemia values (G0, GI, GP, G30, G60) during the electrogastrographic record between group C1 (deemed to represent a normal electrogastrographic record) and groups C2, C3, C4, where, depending on the percentage distribution of preprandial and postprandial frequencies, patients electrogastrographic records did not comply with the normative criteria. Significant differences between mean glycaemia values were found in the group with glicated haemoglobin values above 7.5%. Although group C3 demonstrated much higher mean glycaemia values in the range HbA1c > 7.5% (by a factor of 1.67), in group C2 the difference of mean glycaemia values in both ranges of glicated haemoglobin values was 1.09. It proves that the statistically significant difference of mean glycaemia values between group C1 and groups C2, C3, C4 for glicated haemoglobin above 7.5% was not only due to differences of mean glycaemia values depending on the haemoglobin value. In other words, the statistically significant difference in mean values between the groups does not only arise out of the fact that patients from the glicated haemoglobin range in excess of 7.5% represent a group of patients with higher mean glycaemia values. Another proof that there is no direct relationship is the insignificance of the differences of mean glycaemia values between groups C2 and C3, C2 and C4, C3 and C4 irrespective of the glicated haemoglobin value.
CONCLUSION. Thus, it seems that momentary glycaemia values during the electrogastrographic record do not demonstrate any effect on the electrogastrographic parameters when its values are correct. On the other hand, such effect is visible with an incorrect electrogastrographic record, and is seen more clearly when the glicated haemoglobin value is considered.
Keywords: electrogastrographydiabetes mellitusglycaemiaHbA1cautonomic neuropathy