Management of diabetes in patients after total pancreatectomy

Abstract

Total pancreatectomy results in diabetes needing insulin administration. The diabetes is rather brittle with high incidence of hypoglycaemia. The basal treatment is intensive insulin therapy. In the present "transplant era", there is the possibility of curing apancreatic diabetes using autologic islets transplantation, especially in patients operated for chronic pancreatitis. This article summarizes the current methods of treatment of patients after total pancreatectomy.