Vol 8, No 8-9 (2007): Practical Diabetology
Review article
Published online: 2007-09-08
Osteoporosis in diabetes mellitus - a risk factor for fractures
Diabetologia Praktyczna 2007;8(8-9):341-348.
Abstract
It is of major clinical importance to establish diagnostic
procedures and treatment modalities in Poland
to prevent osteoporotic fractures. Diabetes
mellitus has been included in the multidisciplinary
management guidelines to prevent bone fractures.
Osteoporosis in type 1 diabetes mellitus is frequently
the first symptom of bone density disorders which
aggravate with age. Uncontrolled diabetes mellitus
is the leading risk factor. In type 2 diabetes mellitus
the etiology of osteoporosis is complex and related
to protective factors such as insulin resistance and
hyperinsulinism, and resorption such as hypercortisolemia
in obesity. In both types of diabetes fracture
rate is increased due to uncontrolled diabetes,
complications, slow bone turnover and altered bone
architecture. Diabetic patients should undergo screening
using heel bone ultrasound (Achilles device)
because of associated peripheral neuropathy and
local osteoporosis.
Keywords: osteoporosis in type 1 and 2 diabetes mellitusbone fracturesprevention and treatment of osteoporosis