open access

Vol 9, No 3-4 (2008): Practical Diabetology
Review articles (submitted)
Published online: 2008-07-04
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Opinions on the role of chromium (III) in the prevention and control of diabetes

Ewelina Król, Zbigniew Krejpcio
Diabetologia Praktyczna 2008;9(3-4):168-175.

open access

Vol 9, No 3-4 (2008): Practical Diabetology
Review articles (submitted)
Published online: 2008-07-04

Abstract

In this work the review of the literature about the role of chromium (III) in prevention and control of diabetes was presented. Studies indicate that Cr (III) is necessary for regulatation of carbohydrate and lipid metabolism mainly due to increasing the number of insulin receptors and its activation by phosphorylation. Some authors believe that chromium (III) deficiency can lead to glucose intolerance and symptoms of type 2 diabetes. Moreover, in type 2 diabetic patients tissular chromium levels may be decreased, therefore some authors recommend chromium supplementation. The animal and human studies in that subject as well as factors affecting chromium supplementation were discussed. However, due to methodological limitations of many clinical studies, the statements of major diabetes associations concerning recommendation from chromium supplementation in individuals with diabetes and obesity still remains negative.

Abstract

In this work the review of the literature about the role of chromium (III) in prevention and control of diabetes was presented. Studies indicate that Cr (III) is necessary for regulatation of carbohydrate and lipid metabolism mainly due to increasing the number of insulin receptors and its activation by phosphorylation. Some authors believe that chromium (III) deficiency can lead to glucose intolerance and symptoms of type 2 diabetes. Moreover, in type 2 diabetic patients tissular chromium levels may be decreased, therefore some authors recommend chromium supplementation. The animal and human studies in that subject as well as factors affecting chromium supplementation were discussed. However, due to methodological limitations of many clinical studies, the statements of major diabetes associations concerning recommendation from chromium supplementation in individuals with diabetes and obesity still remains negative.
Get Citation

Keywords

diabetes; chromium; supplementation

About this article
Title

Opinions on the role of chromium (III) in the prevention and control of diabetes

Journal

Clinical Diabetology

Issue

Vol 9, No 3-4 (2008): Practical Diabetology

Pages

168-175

Published online

2008-07-04

Bibliographic record

Diabetologia Praktyczna 2008;9(3-4):168-175.

Keywords

diabetes
chromium
supplementation

Authors

Ewelina Król
Zbigniew Krejpcio

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