open access

Vol 9, No 3-4 (2008): Practical Diabetology
Review articles (submitted)
Published online: 2008-07-04
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Diabetes of type LADA - definition, diagnostics and treatment

Malgorzata Szelachowska
Diabetologia Praktyczna 2008;9(3-4):145-151.

open access

Vol 9, No 3-4 (2008): Practical Diabetology
Review articles (submitted)
Published online: 2008-07-04

Abstract

LADA is a form of autoimmune-mediated diabetes inadults. The progression of beta-cell failure is slower than in childhood type 1 diabetes. Patients with LADA present with more preserved beta-cell function than hose with classic type1 diabetes. The diagnosis of LADA according to Immunology Diabetes Society is based on three features: age over 35 years, the presence at least one of four circulating autoantibodies to pancreatic islet cell antigens and lack of requirement for insulin at least 6 month after diagnosis. The level of C-peptide secretion after stimulation with intravenous helped to diagnosis. There are different opinions in relation to treatmen of LADA. Some studies sugest, that insulin treatment is indicated at time of diagosis LADA, some of them - when patients upon failure of oral hypoglycemic treatment.

Abstract

LADA is a form of autoimmune-mediated diabetes inadults. The progression of beta-cell failure is slower than in childhood type 1 diabetes. Patients with LADA present with more preserved beta-cell function than hose with classic type1 diabetes. The diagnosis of LADA according to Immunology Diabetes Society is based on three features: age over 35 years, the presence at least one of four circulating autoantibodies to pancreatic islet cell antigens and lack of requirement for insulin at least 6 month after diagnosis. The level of C-peptide secretion after stimulation with intravenous helped to diagnosis. There are different opinions in relation to treatmen of LADA. Some studies sugest, that insulin treatment is indicated at time of diagosis LADA, some of them - when patients upon failure of oral hypoglycemic treatment.
Get Citation

Keywords

LADA; diabetes mellitus; diagnosis; treatment

About this article
Title

Diabetes of type LADA - definition, diagnostics and treatment

Journal

Clinical Diabetology

Issue

Vol 9, No 3-4 (2008): Practical Diabetology

Pages

145-151

Published online

2008-07-04

Bibliographic record

Diabetologia Praktyczna 2008;9(3-4):145-151.

Keywords

LADA
diabetes mellitus
diagnosis
treatment

Authors

Malgorzata Szelachowska

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