open access

Vol 10, No 2 (2009): Practical Diabetology
Review articles (submitted)
Published online: 2009-06-25
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A relationship between periodontal diseases, diabetes mellitus and diabetic nephropathy

Beata Wożakowska-Kapłon, Krzysztof J. Filipiak, Grzegorz Opolski, Renata Górska
Diabetologia Praktyczna 2009;10(2):72-75.

open access

Vol 10, No 2 (2009): Practical Diabetology
Review articles (submitted)
Published online: 2009-06-25

Abstract

Diabetes mellitus is a metabolic disease estimated to affect over 5% of adult population. Among the late complications associated to the diabetes mellitus, periodontal disease has been highlighted, and it can be more severe and refractory to treatment than in healthy subjects. Periodontal disease is a microbe-induced chronic inflammatory condition that leads to gingival inflammation, periodontal tissue destruction, and alveolar bone loss. Certain anaerobic gram-negative bacteria within the plaque biofilm are the major etiological agents of periodontal disease. The host response in periodontal disease is characterized by the production of inflammatory mediators, cytokines and matrix metalloproteinases. Both hyper- and hypoglycemia influence on periodontal tissue condition. Poorly controlled diabetes mellitus leads to alveolar bone loss, loss of attachement and periodontal tissue destruction. An periodontal disease affects on worsening of glycemic control. There exists two-way relationship between both diseases.

Abstract

Diabetes mellitus is a metabolic disease estimated to affect over 5% of adult population. Among the late complications associated to the diabetes mellitus, periodontal disease has been highlighted, and it can be more severe and refractory to treatment than in healthy subjects. Periodontal disease is a microbe-induced chronic inflammatory condition that leads to gingival inflammation, periodontal tissue destruction, and alveolar bone loss. Certain anaerobic gram-negative bacteria within the plaque biofilm are the major etiological agents of periodontal disease. The host response in periodontal disease is characterized by the production of inflammatory mediators, cytokines and matrix metalloproteinases. Both hyper- and hypoglycemia influence on periodontal tissue condition. Poorly controlled diabetes mellitus leads to alveolar bone loss, loss of attachement and periodontal tissue destruction. An periodontal disease affects on worsening of glycemic control. There exists two-way relationship between both diseases.
Get Citation

Keywords

periodontal diseases; diabetes mellitus

About this article
Title

A relationship between periodontal diseases, diabetes mellitus and diabetic nephropathy

Journal

Clinical Diabetology

Issue

Vol 10, No 2 (2009): Practical Diabetology

Pages

72-75

Published online

2009-06-25

Bibliographic record

Diabetologia Praktyczna 2009;10(2):72-75.

Keywords

periodontal diseases
diabetes mellitus

Authors

Beata Wożakowska-Kapłon
Krzysztof J. Filipiak
Grzegorz Opolski
Renata Górska

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