Vol 10, No 5 (2009): Practical Diabetology
Review article
Published online: 2010-01-07
Selected aspects of pancreas transplantation in patients with type I diabetes mellitus. Based on reports from the 14th Congress of the European Society for Organ Transplantation in Paris in 2009
Diabetologia Praktyczna 2009;10(5):202-208.
Abstract
Although the number of pancreas transplantations
performed worldwide in patients with type I diabetes
mellitus complications exceeded 28,000, difficulties
related to this organ transplantation remain
a challenge for modern transplantation medicine.
Constant organs shortage forces transplant teams
to transplant pancreata previously not accepted.
Older recipients with long lasting diabetes mellitus
referred to transplantation require more careful preoperative
diagnostics. Due to asymptomatic course
of the majority of pancreas rejection episodes and
low specificity of laboratory markers of this process,
in order to estimate lesions in transplanted organ
biopsy is performed more and more often. Intraabdominal
infections that develop after pancreas transplantation
are still severe hazard to transplanted patient.
Worse results observed in patients who lost
pancreatic graft are the reason of considering retransplantation
of the pancreas. On the other hand constant progress in the field of immunosuppression
allows for application of treatment protocols
adjusted to individual requirements of the patient.
The aim of the paper is to present problems related
to solid pancreas transplantation presented at the
14. Congress of the European Society for Organ
Transplantation in Paris in 2009.
Keywords: pancreas transplantationtype I diabetes mellituspancreas transplantation alonesimultaneous pancreas and kidney transplantationpancreas after kidney transplantation