Post-occlusion hyperemia test in microcirculation assessment in short-time diabetic patients type 2 by using laser-Doppler fluxometry

Abstract

INTRODUCTION. The aim of this study was to asses microvascular response by using post-occlusion hyperemic test in short-time diabetic patients. These test by using laser-Doppler effect is very useful and acceptable method in diagnostic of microcirculation.
MATERIAL AND METHODS. The study group consisted of 61 patients (122 lower limb); 33 men and 28 women with diabetes mellitus type 2. The average duration of diabetes was 2.9 years ± 1.8 SD. The diabetic group consisted of 31 patients. The control group consisted of 30 healthy patients, age and gender-matched to diabetic group. Microvascular research was done using laser-Doppler fluxometry. During the examination 3-minutes occlusion of the lower limb was performed using a cuff, placed directly over the knee. The measurements were assessed from the top of hallux, left than right foot, one pointed scanner.
RESULTS. Six parameters occlusion test was assessed. We observed some differences between diabetic and the control groups. Parameter TH-half time of hyperemia - was significantly higher in diabetic group than in the control.
CONCLUSIONS. The best post-occlusion parameters are: is TM-time of peak flow and especially TH-half-time of hyperemia response. Post-occlusion hyperemia test is very important complement trial in classical medical examination. It is worth to say that post-occlusion test is absolutely non-invasive and safe for patients.
(Diabet. Prakt. 2010; 11, 1: 1-8)