Vol 11, No 6 (2010): Practical Diabetology
Case report
Published online: 2011-02-16
Hyperosmolar hyperglycemic syndrome in patient with bipolar disorder
Diabetologia Praktyczna 2010;11(6):230-233.
Abstract
Hyperosmolar hyperglycemic syndrome is one of
acute complications of diabetes. It usually appears
in type 2 diabetics, when insulin secretion by
pancreatic beta cells is sufficient to prevent lipolysis
and ketogenesis. It is however inadequate to
maintain normoglycemia. Conditions of excessive
release of counterregulatory hormones may lead to
this complication. The onset of hyperosmolar
hyperglycemic syndrome may be also directly or
indirectly dependent on current therapy. Lithium
used in treatment of depressive states may worsen
hyperglycemia by impairing kidney-regulated water
homeostasis. (Diabet. Prakt. 2010; 11, 6: 230–234)
Keywords: hyperosmolar hyperglycemic syndromelithiumdiabetes insipidus