open access

Vol 2, No 4 (2013)
Review
Published online: 2013-09-03
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Metformin — new reimbursement indications

Krzysztof Strojek, Marta Wróbel, Aleksandra Szymborska-Kajanek, Dominika Rokicka
Diabetologia Kliniczna 2013;2(4):120-124.

open access

Vol 2, No 4 (2013)
Review
Published online: 2013-09-03

Abstract

The aim of this article is to describe mechanisms of metformin action and advantages of its use in otherindications than type 2 diabetes. Prediabetes, metabolic syndrome are not mild disorders and there is a need for action to prevent or delay diagnosis of diabetes in future. Modification of lifestyle is of key importance,however it is rarely implemented with success by patients. In such cases use of metformin should be considered.This drug for many years is used in treatment of polycystic ovary syndrome. By reduction of insulin resistance and secondary hyperinsulinemia in patients with PCOS metformin diminishes androgenesis in ovaries.

Abstract

The aim of this article is to describe mechanisms of metformin action and advantages of its use in otherindications than type 2 diabetes. Prediabetes, metabolic syndrome are not mild disorders and there is a need for action to prevent or delay diagnosis of diabetes in future. Modification of lifestyle is of key importance,however it is rarely implemented with success by patients. In such cases use of metformin should be considered.This drug for many years is used in treatment of polycystic ovary syndrome. By reduction of insulin resistance and secondary hyperinsulinemia in patients with PCOS metformin diminishes androgenesis in ovaries.
Get Citation

Keywords

metformin, treatment, PCOS, prediabetes, metabolic syndrome

About this article
Title

Metformin — new reimbursement indications

Journal

Clinical Diabetology

Issue

Vol 2, No 4 (2013)

Pages

120-124

Published online

2013-09-03

Bibliographic record

Diabetologia Kliniczna 2013;2(4):120-124.

Keywords

metformin
treatment
PCOS
prediabetes
metabolic syndrome

Authors

Krzysztof Strojek
Marta Wróbel
Aleksandra Szymborska-Kajanek
Dominika Rokicka

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