Diabetes and the risk of prostate cancer

Abstract

Diabetes mellitus (DM) is one of the fastest deadly
growing diseases around the world and prostate cancer (CaP) is one of the most common types of
cancer among men and it has the highest mortality
after lung cancer in the United States of America
(USA). It is interesting that epidemiologic evidence
suggests that the occurrence of DM is related to
a decreased CaP risk. The cause of this association
remains largely unknown. DM and CaP are influenced
by many factors, e.g.: environmental, hormonal,
immunological and genetic. The aim of this study
was to underline the role of certain factors that
may influence the inverse relationship between
prostate cancer and diabetes and to asses the
currently proposed hypotheses for understanding
the mecha-nism of this process.