open access

Vol 12, No 5 (2011): Practical Diabetology
Review paper
Published online: 2011-12-29
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Bromokryptyna — stary lek w nowej formule skutecznym sposobem leczenia cukrzycy typu 2

Magdalena Pertyńska-Marczewska, Katarzyna Cypryk
Diabetologia Praktyczna 2011;12(5):175-179.

open access

Vol 12, No 5 (2011): Practical Diabetology
Review articles (submitted)
Published online: 2011-12-29

Abstract

Quick-release bromocriptine mesylate was approved by the Food and Drug Administration (FDA) in May 2009, for the treatment of type 2 diabetes (T2DM). The quick-release formulation of bromocriptine (bromocriptine- QR; Cycloset) represents a novel therapeutic option in T2DM by targeting centrally mediated pathways of glucose metabolism, effecting in reducing plasma glucose, triglycerides, free fatty acid (FFA) levels and eventually cardiovascular events. Randomized controlled trials have shown that bromocriptine- QR lowers glycated hemoglobin by 0.4– –0.8% either as monotherapy or in combination with other anti-diabetes medications. Bromocriptine-QR mechanism of action, unique formulation, clinical efficacy and safety, proves it to be a great alternative to current treatments for type 2 diabetes. (Diabet. Prakt. 2011; 12, 5: 175–179)

Abstract

Quick-release bromocriptine mesylate was approved by the Food and Drug Administration (FDA) in May 2009, for the treatment of type 2 diabetes (T2DM). The quick-release formulation of bromocriptine (bromocriptine- QR; Cycloset) represents a novel therapeutic option in T2DM by targeting centrally mediated pathways of glucose metabolism, effecting in reducing plasma glucose, triglycerides, free fatty acid (FFA) levels and eventually cardiovascular events. Randomized controlled trials have shown that bromocriptine- QR lowers glycated hemoglobin by 0.4– –0.8% either as monotherapy or in combination with other anti-diabetes medications. Bromocriptine-QR mechanism of action, unique formulation, clinical efficacy and safety, proves it to be a great alternative to current treatments for type 2 diabetes. (Diabet. Prakt. 2011; 12, 5: 175–179)
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Keywords

bromocriptine; quick release formulation; diabetes; insulin resistance; cardiovascular risk

About this article
Title

Bromokryptyna — stary lek w nowej formule skutecznym sposobem leczenia cukrzycy typu 2

Journal

Clinical Diabetology

Issue

Vol 12, No 5 (2011): Practical Diabetology

Article type

Review paper

Pages

175-179

Published online

2011-12-29

Bibliographic record

Diabetologia Praktyczna 2011;12(5):175-179.

Keywords

bromocriptine
quick release formulation
diabetes
insulin resistance
cardiovascular risk

Authors

Magdalena Pertyńska-Marczewska
Katarzyna Cypryk

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