open access

Ahead of print
Case report
Published online: 2024-02-21
Get Citation

Squamous cell carcinoma abdominal cavity of unknown primary site - diagnostic difficulties and treatment.

Krzysztof Kowalik1, Marta Suchomska1, Katarzyna Hetman2, Andrzej Modrzejewski1
Affiliations
  1. Oddział Kliniczny Chirurgii Ogólnej Pomorskiego Uniwersytetu Medycznego
  2. Oddział Onkologii Klinicznej Zachodniopomorskiego Centrum Onkologii w Szczecinie

open access

Ahead of print
Case reports
Published online: 2024-02-21

Abstract

The authors present the case of a patient with advanced squamous cell carcinoma of unknown starting point. The patient was found to have a hernia in the scar from a previous cesarean section, which was plastinated. Tissue was removed, which was evaluated as necrosis of the web in the hernia sac. No histopathological examination of the removed tissues was performed. After the operation 6 months, the leakage of pus from the surgical scar persisted. After 6 months, a tumor was found in the lower abdomen several centimeters in size. At the edge of the ulcer located in the surgical scar, sections were taken and the tumor was found to be squamous cell carcinoma. On tk examination, the tumor measures 98 mm x 65 mm x 156 mm. Surgical treatment was undertaken involving removal of the tumor and abdominal plasty. After surgery, CTH was implemented. The patient is so far without recurrence.

Abstract

The authors present the case of a patient with advanced squamous cell carcinoma of unknown starting point. The patient was found to have a hernia in the scar from a previous cesarean section, which was plastinated. Tissue was removed, which was evaluated as necrosis of the web in the hernia sac. No histopathological examination of the removed tissues was performed. After the operation 6 months, the leakage of pus from the surgical scar persisted. After 6 months, a tumor was found in the lower abdomen several centimeters in size. At the edge of the ulcer located in the surgical scar, sections were taken and the tumor was found to be squamous cell carcinoma. On tk examination, the tumor measures 98 mm x 65 mm x 156 mm. Surgical treatment was undertaken involving removal of the tumor and abdominal plasty. After surgery, CTH was implemented. The patient is so far without recurrence.
Get Citation

Keywords

squamous cell carcinoma; carcinoma of unknown primary site; cancer metastases; lymph nodes, chemioterapy

About this article
Title

Squamous cell carcinoma abdominal cavity of unknown primary site - diagnostic difficulties and treatment.

Journal

Chirurgia Polska (Polish Surgery)

Issue

Ahead of print

Article type

Case report

Published online

2024-02-21

Page views

52

Article views/downloads

77

Keywords

squamous cell carcinoma
carcinoma of unknown primary site
cancer metastases
lymph nodes
chemioterapy

Authors

Krzysztof Kowalik
Marta Suchomska
Katarzyna Hetman
Andrzej Modrzejewski

References (18)
  1. Pavlidis N, Briasoulis E, Hainsworth J, et al. Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer. 2003; 39(14): 1990–2005.
  2. Matsubara N, Mukai H, Nagai S, et al. Review of primary unknown cancer: cases referred to the National Cancer Center Hospital East. Int J Clin Oncol. 2010; 15(6): 578–582.
  3. Wang Y, He SS, Bao Y, et al. Cervical lymph node carcinoma metastasis from unknown primary site: a retrospective analysis of 154 patients. Cancer Med. 2018; 7(5): 1852–1859.
  4. Pavlidis N, Fizazi K. Carcinoma of unknown primary (CUP). Crit Rev Oncol Hematol. 2009; 69(3): 271–278.
  5. Kwee TC, Kwee RM. Combined FDG-PET/CT for the detection of unknown primary tumors: systematic review and meta-analysis. Eur Radiol. 2009; 19(3): 731–744.
  6. Dorobisz K, Wlodarska-Polinska I, Pazdro-Zastawny K, et al. The impact of the patient's condition, diagnostic procedures and treatment on the survival of carcinoma of unknown primary site patients. Cancer Manag Res. 2019; 11: 6603–6614.
  7. Koivunen P, Bäck L, Laranne J, et al. Unknown primary: diagnostic issues in the biological endoscopy and positron emission tomography scan era. Curr Opin Otolaryngol Head Neck Surg. 2015; 23(2): 121–126.
  8. Nabili V, Zaia B, Blackwell KE, et al. Positron emission tomography: poor sensitivity for occult tonsillar cancer. Am J Otolaryngol. 2007; 28(3): 153–157.
  9. Hayashi T, Muto M, Hayashi R, et al. Usefulness of narrow-band imaging for detecting the primary tumor site in patients with primary unknown cervical lymph node metastasis. Jpn J Clin Oncol. 2010; 40(6): 537–541.
  10. Rades D, Kühnel G, Wildfang I, et al. Localised disease in cancer of unknown primary (CUP): the value of positron emission tomography (PET) for individual therapeutic management. Ann Oncol. 2001; 12(11): 1605–1609.
  11. Zhu L, Wang N. 18F-fluorodeoxyglucose positron emission tomography-computed tomography as a diagnostic tool in patients with cervical nodal metastases of unknown primary site: a meta-analysis. Surg Oncol. 2013; 22(3): 190–194.
  12. Guardiola E, Chaigneau L, Villanueva C, et al. Is there still a role for triple endoscopy as part of staging for head and neck cancer? Curr Opin Otolaryngol Head Neck Surg. 2006; 14(2): 85–88.
  13. Pentheroudakis G, Golfinopoulos V, Pavlidis N. Switching benchmarks in cancer of unknown primary: from autopsy to microarray. Eur J Cancer. 2007; 43(14): 2026–2036.
  14. Petrakis D, Pentheroudakis G, Voulgaris E, et al. Prognostication in cancer of unknown primary (CUP): development of a prognostic algorithm in 311 cases and review of the literature. Cancer Treat Rev. 2013; 39(7): 701–708.
  15. Briasoulis E, Pavlidis N, Felip E, et al. ESMO Guidelines Working Group. Cancers of unknown primary site: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol. 2009; 20(Suppl 4): 154–155.
  16. Al Kadah B, Papaspyrou G, Linxweiler M, et al. Cancer of unknown primary (CUP) of the head and neck: retrospective analysis of 81 patients. Eur Arch Otorhinolaryngol. 2017; 274(6): 2557–2566.
  17. Christiansen H, Hermann RM, Martin A, et al. Neck lymph node metastases from an unknown primary tumor retrospective study and review of literature. Strahlenther Onkol. 2005; 181(6): 355–362.
  18. Zhang Y, Chen BO, Zhu J, et al. Squamous cell carcinoma of unknown primary site presenting with an abdominal wall lesion as the primary symptom: A case report and review of the literature. Oncol Lett. 2015; 10(4): 2161–2165.

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Via MedicaBy Via Medicav Group sp. z o.o., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl