Introduction: Diabetes is a chronic disease that leads to various complications. Through complex diabetic care and effective therapy, it is possible, though, to control and actively influence the sufferers subjective experience and quality of life. The aim of study was an evaluation on influence of the risk factors on domains of quality of life in type 2 diabetes patients.

Material and methods: The subjects of the study were 101 diabetic patients suffering from type 2 diabetes, complicated by peripheral arterial disease (diabetic macroangiopathy), at the stage of Fontaine stage II ischemia. Each patients who qualified for the study was evaluated with SF-36 questionnaire evaluating general quality of life and with the authors own survey which takes into consideration the specific nature of the disease. In the statistical analysis basic statistical tests were used, t-Student test, Chi-square test, Wilcoxon test, Kruskal-Wallis and U Mann-Whitney test.

Results: In the group I, the multi-factor analysis of predictors influencing evaluation of quality of life of the surveyed patients revealed statistically significant correlation between domains role-physical (RP), physical functioning (PF) and vitality (VT) and age, disease duration and pain, in the mental health (MH) domain with age, pain and in social functioning (SF) it correlated with pain. In the second group, the multi-factoral analysis showed statistically significant correlation between the following domains: PF domain and age, disease duration and pain intensity, VT domain and pain intensity, MH domain and body mass index (BMI) and age, BMI index and disease duration in SF domain.

Conclusions: The group of patients treated with insulin evaluated their quality of life lower. The kind of treatment way did not influence on the quality of life. The important determination could be disease duration or obesity.