Vol 3, No 4 (2001)
Published online: 2002-04-25
The healing process of the dallon vascular prosthesis in the human arterial system. Morphological analysis of the material obtained during autopsy
Chirurgia Polska 2001;3(4):179-188.
Abstract
Introduction: The aim of the study was to conduct morphological analyses of the healing process of Dallon vascular prostheses implanted in the human arterial system, obtained for examination after patient’s decease.
Material and methods: 40 Dallon straight and bifurcated vascular prostheses implanted in different locations of the arterial system obtained during autopsy were analysed. The prostheses were collected not later than 72 hours after the decease. The time between the implantation of the prosthesis and patient’s death varied from 2 days to 10 years 4 months (23.3 months on average). The graft specimens were examined macroscopically and microscopically.
Results: Analyses of the morphological images of the inner layer covering the vascular prosthesis during its patency show that on its surface reparation and synthesis process takes place all the time. The inner layer is not covered with endothelial or endothelial-like cells, although the prosthesis stays patent.
Conclusions: 1. The internal layer of the vascular prosthesis in the human arterial system is not covered by endothelium. 2. Despite the lack of endothelium, the prosthesis patency is preserved even after many years of functioning. 3. All the time during the implant’s functioning in the human body, reparation and synthesis processes are continuing on both surfaces of the prosthesis. 4. The prosthesis infection has an influence on the prosthesis fibre coil stability, causing its loosening.
Material and methods: 40 Dallon straight and bifurcated vascular prostheses implanted in different locations of the arterial system obtained during autopsy were analysed. The prostheses were collected not later than 72 hours after the decease. The time between the implantation of the prosthesis and patient’s death varied from 2 days to 10 years 4 months (23.3 months on average). The graft specimens were examined macroscopically and microscopically.
Results: Analyses of the morphological images of the inner layer covering the vascular prosthesis during its patency show that on its surface reparation and synthesis process takes place all the time. The inner layer is not covered with endothelial or endothelial-like cells, although the prosthesis stays patent.
Conclusions: 1. The internal layer of the vascular prosthesis in the human arterial system is not covered by endothelium. 2. Despite the lack of endothelium, the prosthesis patency is preserved even after many years of functioning. 3. All the time during the implant’s functioning in the human body, reparation and synthesis processes are continuing on both surfaces of the prosthesis. 4. The prosthesis infection has an influence on the prosthesis fibre coil stability, causing its loosening.
Keywords: humanvascular prosthesishealingmorphologyautopsymicroscopyhistology
