open access

Vol 6, No 4 (2004)
Aktualności
Published online: 2005-01-26
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Gastrointestinal stromal tumors (GIST)

Maciej Zaniewski, Zbigniew Smyła, Piotr Piekorz, Joanna Straszecka, Eugeniusz Majewski, Czesław Marcisz, Paweł Jedynak, Krzysztof Nitecki, Zbigniew Antosz
Chirurgia Polska 2004;6(4):253-259.

open access

Vol 6, No 4 (2004)
Aktualności
Published online: 2005-01-26

Abstract

Gastrointestinal stromal tumors (GIST) originate from the mezenchymal tissue of gastrointestinal tract, most probably from interstitial (Cajal) cells. Being the most common mesenchymal malignancy, GISTs concern no more than 1% of all gastrointestinal neoplasmatic tumors. Stromal tumors appear in the elderly and are usually located in the stomach (70%) and the small intestine (20–30%). About 30% of GISTs are malignant with signs of organ infiltration or with the presence of distant metastases. The presence of the membrane protein KIT (positive reaction against CD 117 in immunohistochemistry) in histological material is the essential factor for the GIST diagnosis. Surgery is the most important method in the treatment of GISTs. The paper presents the authors’ own experience concerning 4 patients with gastrointestinal stromal tumors treated surgically.

Abstract

Gastrointestinal stromal tumors (GIST) originate from the mezenchymal tissue of gastrointestinal tract, most probably from interstitial (Cajal) cells. Being the most common mesenchymal malignancy, GISTs concern no more than 1% of all gastrointestinal neoplasmatic tumors. Stromal tumors appear in the elderly and are usually located in the stomach (70%) and the small intestine (20–30%). About 30% of GISTs are malignant with signs of organ infiltration or with the presence of distant metastases. The presence of the membrane protein KIT (positive reaction against CD 117 in immunohistochemistry) in histological material is the essential factor for the GIST diagnosis. Surgery is the most important method in the treatment of GISTs. The paper presents the authors’ own experience concerning 4 patients with gastrointestinal stromal tumors treated surgically.
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Keywords

stromal tumors; GIST; diagnosis; treatment

About this article
Title

Gastrointestinal stromal tumors (GIST)

Journal

Chirurgia Polska (Polish Surgery)

Issue

Vol 6, No 4 (2004)

Pages

253-259

Published online

2005-01-26

Bibliographic record

Chirurgia Polska 2004;6(4):253-259.

Keywords

stromal tumors
GIST
diagnosis
treatment

Authors

Maciej Zaniewski
Zbigniew Smyła
Piotr Piekorz
Joanna Straszecka
Eugeniusz Majewski
Czesław Marcisz
Paweł Jedynak
Krzysztof Nitecki
Zbigniew Antosz

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