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Evaluation of interleukin 6 and interleukin 10 serum levels in patients with acute pancreatitis
open access
Abstract
Material and methods: This study included 21 patients with mild acute pancreatitis (AP) and 13 patients with severe AP, with 3 deaths among them. Serum levels of IL-6 and IL-10 were determined on the day of admission (1 day) and on day 3 of the patient’s hospital stay.
Results: Serum levels of IL-6 and IL-10 were higher in severe acute pancreatitis both on the 1st and the 3rd day of hospitalization. The highest levels of both interleukins were observed among patients who died because of acute pancreatitis.
Conclusions: The evaluation of IL-6 and IL-10 serum levels indicates their great value in prognosticating severe acute pancreatitis and an unfavorable lethal outcome of disease.
Abstract
Material and methods: This study included 21 patients with mild acute pancreatitis (AP) and 13 patients with severe AP, with 3 deaths among them. Serum levels of IL-6 and IL-10 were determined on the day of admission (1 day) and on day 3 of the patient’s hospital stay.
Results: Serum levels of IL-6 and IL-10 were higher in severe acute pancreatitis both on the 1st and the 3rd day of hospitalization. The highest levels of both interleukins were observed among patients who died because of acute pancreatitis.
Conclusions: The evaluation of IL-6 and IL-10 serum levels indicates their great value in prognosticating severe acute pancreatitis and an unfavorable lethal outcome of disease.
Keywords
acute pancreatitis; interleukin-6; interleukin-10


Title
Evaluation of interleukin 6 and interleukin 10 serum levels in patients with acute pancreatitis
Journal
Chirurgia Polska (Polish Surgery)
Issue
Pages
221-229
Published online
2005-01-26
Bibliographic record
Chirurgia Polska 2004;6(4):221-229.
Keywords
acute pancreatitis
interleukin-6
interleukin-10
Authors
Justyna Cielecka
Jerzy Badowski
Jacek Cywiński
Jacek Śmigielski
Joanna Ulańska
Krzysztof Kołomecki