Vol 7, No 2 (2005)
Published online: 2005-09-06
Introduction of simultaneous pancreas and kidney transplantation programme in Upper Silesia
Chirurgia Polska 2005;7(2):105-112.
Abstract
Background: Simultaneous pancreas and kidney transplantation (SPK) is considered as the best method
of treatment of patients with chronic renal failure (CRF) and insulin dependent diabetes mellitus (IDDM).
The aim of this study is to present the results of the SPK programme 1 year after introduction at the
transplant centre in Katowice.
Material and methods: Five SPK were performed between April 2004 and April 2005. The recipients’ age was 30 to 38 years, duration of IDDM - 19 to 33 years and duration of dialysis therapy - 6 to 26 months. A pancreatic graft was revascularized by a Y-graft anastomosed to the recipient’s iliac artery and portal vein anastomosed to the vena cava inferior. The pancreatic juice was drained using a duodenal segment anastomosed to the jejunum distal to the Treitz ligament. The kidney was transplanted using the standard technique. All patients received a triple immunosupression regimen composed of tacrolimus or cyclosporin A, mycophenolate mofetil and steroids.
Results: At present all patients are alive with well-functioning kidney and pancreatic grafts (serum creatinine at discharge from hospital was 93-160 µmol/l and serum glucose was 3.8-5.8 mmol/l). Surgical complications were observed in 2 patients: haemorrhage requiring early relaparotomy and wound suppuration.
Material and methods: Five SPK were performed between April 2004 and April 2005. The recipients’ age was 30 to 38 years, duration of IDDM - 19 to 33 years and duration of dialysis therapy - 6 to 26 months. A pancreatic graft was revascularized by a Y-graft anastomosed to the recipient’s iliac artery and portal vein anastomosed to the vena cava inferior. The pancreatic juice was drained using a duodenal segment anastomosed to the jejunum distal to the Treitz ligament. The kidney was transplanted using the standard technique. All patients received a triple immunosupression regimen composed of tacrolimus or cyclosporin A, mycophenolate mofetil and steroids.
Results: At present all patients are alive with well-functioning kidney and pancreatic grafts (serum creatinine at discharge from hospital was 93-160 µmol/l and serum glucose was 3.8-5.8 mmol/l). Surgical complications were observed in 2 patients: haemorrhage requiring early relaparotomy and wound suppuration.
Keywords: pancreas and kidney transplantationinsulin dependent diabetes mellituschronic renal failure
