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Estimation of matrix metalloproteinase 2 (MMP-2) blood levels in patients with groin hernia
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Abstract
Material and methods: The study was performed in a group of 70 patients, male, aged 25-74 years (mean 52) with groin hernia. The control group comprised 10 healthy males aged 30-68 years (mean 46).
Results: In our studies we noticed increased blood concentrations of MMP-2 in patients with groin hernia, both direct and indirect in all age groups. The highest blood levels of MMP-2 were observed in young men with a direct hernia rather than those with an indirect one.
Conclusions: Our research is concurrent with other authors. This study confirms the important role of MMP-2 in the pathogenesis of inguinal hernia. These results suggest that the development of direct inguinal hernia is more genetically dependent than indirect hernia. The pathogenesis of indirect hernia seems to be connected with increased abdominal pressure e.g. during hard work.
Abstract
Material and methods: The study was performed in a group of 70 patients, male, aged 25-74 years (mean 52) with groin hernia. The control group comprised 10 healthy males aged 30-68 years (mean 46).
Results: In our studies we noticed increased blood concentrations of MMP-2 in patients with groin hernia, both direct and indirect in all age groups. The highest blood levels of MMP-2 were observed in young men with a direct hernia rather than those with an indirect one.
Conclusions: Our research is concurrent with other authors. This study confirms the important role of MMP-2 in the pathogenesis of inguinal hernia. These results suggest that the development of direct inguinal hernia is more genetically dependent than indirect hernia. The pathogenesis of indirect hernia seems to be connected with increased abdominal pressure e.g. during hard work.
Keywords
metalloproteinaze 2 (MMP-2); inguinal hernia; transversal fascia


Title
Estimation of matrix metalloproteinase 2 (MMP-2) blood levels in patients with groin hernia
Journal
Chirurgia Polska (Polish Surgery)
Issue
Pages
74-79
Published online
2005-09-06
Page views
494
Article views/downloads
1207
Bibliographic record
Chirurgia Polska 2005;7(2):74-79.
Keywords
metalloproteinaze 2 (MMP-2)
inguinal hernia
transversal fascia
Authors
Maciej Amsolik
Krzysztof Kuzdak
Krzysztof Kołomecki
Jacek Śmigielski
Krzysztof Kopeć
Zbigniew Pasieka
Michał Kusiński