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Vol 7, No 3 (2005)
Published online: 2005-11-07

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Intravascular papillary endothelial hyperplasia in the gallbladder - the first case in the gallbladder

Jacek Pająk, Michał Dyaczyński, Dariusz Gołka, Michał Grzyb, Jacek Starzewski, Ewa Zielińska-Pająk
Chirurgia Polska 2005;7(3):206-210.


Intravascular papillary endothelial hyperplasia (IPEH) is a rare benign proliferation of endothelial cells associated with thrombus organization. It develops in blood vessels as vascular malformations, or benign vascular tumours. The histological picture may mimic vascular sarcoma. A 64 year old female patient with a 4 year history of cholelithiasis was admitted to the ward with signs of biliary colic. An enlarged gallbladder filled with calculi was removed. A histopathological examination of the excised gallbladder revealed intravascular papillary endothelial hyperplasia. In this paper, according to our knowledge, we present the first case of IPEH in vessels of the gallbladder. We believe that in this case an inflammatory factor played an important role in the pathogenesis and development of IPEH.

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Chirurgia Polska (Polish Surgery)