The process of neoangiogenesis in colorectal carcinoma

Abstract

Colorectal carcinoma is still one of the most crucial problems in oncology today. Firstly, this neoplasm occurs frequently and in terms of new cases world wide - at around one million per year - it is second on the list, right after pulmonary carcinoma. Secondly, it is a neoplasm which still has a poor prognosis in which the survival rate over a five-year period, in the majority of cases, is below 50%. Moreover, there are around half a million deaths a year worldwide. In this work, the authors discussed the role of neoangiogenesis in the large intestine cancer pathogenesis.